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由于异烟肼(INH)对结核感染的有效治疗作用,结核病应在很大程度上得以预防,但自1984年以来,美国的结核病患病人数和发病率并没有下降。为明确预防结核病失败的原因,作者对美国亚拉巴马州的伯明翰、旧金山和芝加哥3个卫生部门的结核病发病情况进行了调查,共279例,均经细菌学证实,伯明翰121例,旧金山73例,芝加哥85例,患者年龄1～95岁,平均52.5岁。肺结核占91.6%,肺外结核8.4%.
Tuberculosis should be largely prevented due to the effective treatment of tuberculosis by isoniazid (INH), but since 1984 there have been no declines in the number and incidence of tuberculosis in the United States. In order to clarify the reasons for the failure of tuberculosis prevention, the authors investigated the incidence of tuberculosis in three health departments in Birmingham, Alabama, the United States, San Francisco and Chicago. A total of 279 cases were confirmed bacteriologically, 121 in Birmingham and 73 in San Francisco , Chicago 85 cases, patients aged 1 to 95 years, mean 52.5 years old. 91.6% of tuberculosis and 8.4% of extrapulmonary tuberculosis.