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目的 :回顾总结肾脏移植经验、改善临床肾脏移植效果。 方法 :总结 1992年 7月～ 2 0 0 0年 10月1118例肾脏移植的临床资料 ,研究组织配型、器官摘取情况、移植手术、移植并发症、免疫抑制剂等因素对移植效果的影响。 结果 :存活率 :术后 1、3、5年人 /肾存活率分别为 93%/ 91 2 %、80 2 %/ 74 5 %、72 %/ 6 6 1%。超急排斥反应发生率 1 2 %,急性排斥反应发生率 2 3 5 %,慢性排斥反应发生率 16 7%。并发症发生率 5 5 %。死亡率16 6 %。 结论 :①加强供受者组织配型、提高器官摘取以及移植手术质量可以明显提高移植物的存活 ,减少外科并发症的发生 ;②并发症是影响人 /肾长期存活的重要因素 ;③合理应用免疫抑制剂可以延长移植肾的存活 ,减少并发症的发生。
Objective: To review and summarize the experience of kidney transplantation and improve the clinical effect of kidney transplantation. Methods: The clinical data of 1118 cases of renal transplantation from July 1992 to October 2000 were summarized, and the effects of tissue matching, organ harvesting, transplantation operation, transplantation complications and immunosuppressive agents on the transplantation effect were studied . Results: Survival rate: The survival rates of human / kidney at 1, 3 and 5 years postoperatively were 93% / 91 2%, 80 2% / 74 5% and 72% / 6 6 1%, respectively. The incidence of hyperacute rejection was 12%, that of acute rejection was 23.5%, and that of chronic rejection was 16.7%. The complication rate was 55%. The death rate was 16.6%. Conclusion: ①To strengthen the matching of donor and recipient tissues, improve organ harvesting and the quality of transplantation can significantly improve graft survival and reduce the incidence of surgical complications; ② complications are the important factors that affect the long-term survival of human / kidney; ③ reasonable Application of immunosuppressive agents can prolong the survival of renal graft and reduce the incidence of complications.