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为分析巨细胞病毒(CMV)在病毒性肝炎病人中的流行情况及临床特点,用酶联免疫吸附试验法为6411例住院的肝炎病人检测血清抗CMV-IgM,并对比观察115例CMV感染者与192例CMV阴性者的临床症状、体征和肝功能等。结果CMV感染率为1.79%,平均发病年龄33.6岁,男女比为2.13∶1,CMV与肝炎病毒呈二重、三重、四重感染,感染率分别为44.74%、47.37%和7.89%,CMV阳性组发热、消化道症状、肝肿大、B超胆囊改变、丙氨酸转氨酶、天门冬氨酸氨基转移酶、γ-谷酰基转移酶及住院时间均高于或长于CMV阴性组。说明CMV在各型肝炎中均可存在,大多呈二重或多重感染,并可加重病毒性肝炎的病情。
To analyze the prevalence and clinical features of cytomegalovirus (CMV) in patients with viral hepatitis, serum anti-CMV-IgM levels were measured in 6411 hospitalized patients with hepatitis C virus by enzyme-linked immunosorbent assay and compared with 115 CMV-infected patients With 192 cases of CMV negative clinical symptoms, signs and liver function. Results The infection rate of CMV was 1.79% and the average age of onset was 33.6 years. The ratio of male to female was 2.13:1. The infection rates of CMV and hepatitis B virus were double, triple and quadruple. The infection rates were 44.74% 47.37% and 7.89%, CMV-positive fever, gastrointestinal symptoms, hepatomegaly, B-cholecyst changes, alanine aminotransferase, aspartate aminotransferase, γ-glutamyl transferase and hospital stay Were higher or longer than CMV negative group. That CMV can exist in all types of hepatitis, mostly in double or multiple infections, and may aggravate the condition of viral hepatitis.