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目的 :为探讨法安明治疗不稳定型心绞痛 (UA)的疗效。方法 :将 48例新近发生的静息性心绞痛持续时间 >15min的患者随机分组 :A组 2 3例 ,给予口服阿斯匹林、β受体阻滞剂、钙离子拮抗剂及强化极化液加硝酸甘油静滴 ;B组 2 5例给上述治疗再加法安明 5 0 0 0IU ,q12h ,皮下注射。连用 7日。 结果 :A、B两组在住院 7日内再发心绞痛、非致死性心肌梗死、心性死亡分别是 30 %与 12 %、17%与 0、9%与 0 ,总的心性事件发生率为 5 7%与 12 %(P <0 .0 1)。结论 :UA患者急性期用法安明治疗有效、安全和方便。
Objective: To investigate the efficacy of fenamin in the treatment of unstable angina pectoris (UA). Methods: Forty-eight patients with newly-diagnosed rest-angina lasting more than 15 minutes were randomly divided into two groups: group A, aspirin, beta-blocker, calcium antagonist and fortified solution Plus nitroglycerin intravenous infusion; Group B 25 cases to the above treatment plus Ampel 50000U, q12h, subcutaneous injection. Used together on the 7th. Results: In group A and group B, angina pectoris was recurred within 7 days of hospitalization. The incidences of non-fatal myocardial infarction and cardiac death were 30% and 12%, 17% and 0, 9% and 0 respectively. The overall incidence of cardiac events was 57 % And 12% (P <0. 01). Conclusion: UA patients in the acute phase of Amin treatment of effective, safe and convenient.