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本文报告用大剂量免疫球蛋白静脉注射治疗9例慢性炎症性脱髓鞘多发性神经病迅速获显著疗效。全组共9例患者,均符合慢性炎症性脱髓鞘多发性神经病的诊断标准:进展性或复发性,以运动障碍为主,对称性多发性神经病,病程均在4周以上,腱反射减弱或消失,CSF 蛋白细胞分离现象更支持诊断,有对称性颅神经损害和弥漫性周围神经脱髓鞘的神经生理证据。3日内给予静注免疫球蛋白0.4克/kg/日,从每小时40ml 的速度增至100ml。静注7～10天后患者均有改善,若仍有明显的神经症状,可再静注2天。结果发现9例患者治疗后均获改善,而且大多在治疗后第2～4天即开始改善,仅1例在第7天改善。改善的持续时间有6例为7～14个月,3例为1～2个月。剐作用有:乏力、食欲降
This article reports the use of high-dose immunoglobulin intravenous injection of 9 cases of chronic inflammatory demyelinating polyneuropathy rapidly achieved a significant effect. The whole group of 9 patients, all in line with the diagnostic criteria of chronic inflammatory demyelinating polyneuropathy: progressive or recurrent, with dyskinesia, symmetric polyneuropathy, duration of more than 4 weeks, decreased tendon reflex Or disappear, CSF protein cell isolation more support the diagnosis of the phenomenon of symmetrical cranial nerve damage and diffuse peripheral nerve demyelination of neurophysiological evidence. Intravenous immunoglobulin 0.4 g / kg / day was given within 3 days, increasing from 40 ml per hour to 100 ml. After 7 to 10 days of intravenous injection, patients have improved, if there are still obvious neurological symptoms, intravenous infusion of 2 days. The results showed that 9 patients improved after treatment, and most of them started to improve on the 2nd to 4th days after treatment, and only 1 patient improved on the 7th day. The duration of improvement was 6 to 7 to 14 months and 3 to 1 to 2 months.剐 role: fatigue, loss of appetite