论文部分内容阅读
目的:观察肠和煎液对急性放射性肠炎的治疗作用及其机制。方法:将62例急性放射性肠炎患者,随机分为观察组和对照组。2组均予放射治疗,观察组32例予口服肠和煎液治疗,对照组30例予口服诺氟沙星和蒙脱石散治疗。观察2组患者治疗前后肠炎症状,血浆超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)变化。结果:总有效率观察组93.75%,对照组76.67%,2组比较,差异有显著性意义(P<0.05)。治疗后观察组各症状评分均显著低于对照组(P<0.05,P<0.01),观察组血浆SOD及GSH-Px水平显著高于对照组(P<0.05)。结论:肠和煎液治疗急性放射性肠炎疗效确切,其作用机制可能与体内抗氧化防御系统有关。
Objective: To observe the therapeutic effect of intestine and decoction on acute radiation enteritis and its mechanism. Methods: 62 patients with acute radiation enteritis were randomly divided into observation group and control group. Radiotherapy was given in both groups. 32 cases in the observation group were treated with oral intestine decoction and 30 cases in the control group were given norfloxacin and montmorillonite powder. The changes of inflammatory symptoms, plasma superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in two groups before and after treatment were observed. Results: The total effective rate was 93.75% in the observation group and 76.67% in the control group. There was significant difference between the two groups (P <0.05). After treatment, the score of each symptom in the observation group was significantly lower than that in the control group (P <0.05, P <0.01). The levels of SOD and GSH-Px in the observation group were significantly higher than those in the control group (P <0.05). Conclusion: Intestinal and Decoction for the treatment of acute radiation enteritis is effective and its mechanism may be related to the body’s antioxidant defense system.