原发性血小板增多症是一种少见的出血血栓性疾病,其特征为末梢血液中血小板持久地增多,常伴有反复自发性皮肤粘膜出血、血管内血栓形成、脾肿大与粒细胞增多。本病自1920年Digugliemo首次报道以来,迄今约已报告200余例。国内自1959年孟报道以来,现共报告28例。近年,我院内科亦收治1例,现报道如下,并对有关文献作一复习。 Essential thrombocythemia is a rare hemorrhagic thrombotic disease characterized by a persistent increase in peripheral blood platelets, often accompanied by recurrent spontaneous mucocutaneous bleeding, intravascular thrombosis, splenomegaly, and granulocytopenia. Since the first report of Digugliemo in 1920, about 200 cases have been reported so far. Since 1959 Meng reported in China, a total of 28 cases have been reported. In recent years, our hospital internal medicine was also treated in 1 case, are reported below, and a review of the literature.