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由输入血清阳性给血者的血传播的巨细胞病毒(CMV)感染常是亚临床型,但对血清阴性或免疫损伤的受血者能确实发病并致死。故推荐给未成熟新生儿、尤其有感染危险的婴儿只能输血清阴性的血。然而此法昂贵而应用困难,也严格限制了血源的供给,因此作者在澳大利亚用日本生产的“Imugard IG500”滤器除去有CMV潜在感染的白细胞,对预防婴儿输血获得的CMV感染进行了一次多中心对照研究。病例是从墨尔本四家医院的新生儿监护病房自1986,1～1987,3住院婴儿符合条件者登记选择的,对需要输血的婴儿随机分组给“Imugard IG
Blood-borne cytomegalovirus (CMV) infections from seropositive enterovirus donors are often subclinical, but can be confirmed and fatal to seronegative or immunocompromised recipients. It is recommended to immature newborns, in particular, the risk of infection of infants can only lose serum-negative blood. However, this method is expensive and difficult to apply and severely restricts the blood supply. Therefore, the authors removed the potentially infected CMV leukocytes by using the “Imugard IG500” filter manufactured in Japan in Australia and performed more than once to prevent CMV infection in infants Central control study. The cases were enrolled from eligible neonatal care units in four Melbourne hospitals since 1986,1 ~ 1987,3, and infants who needed blood transfusion were randomly assigned to "Imugard IG