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应用酶联免疫法测定25例急性心肌梗塞(AMI)、33例非心肌梗塞(NMI〕和30例正常人血清肌钙蛋白T(TnT)的浓度。结果显示,AMI组12.37±7.17ng/ml.明显高于后两组(P<0.01);正常人组0.04±0.06ng/ml,单侧99%可信上限界为0.19ng/ml,以>0.2ng/ml为阳性,AMI组阳性率100%,而骨骼肌损伤10例无1例阳性。结果表明,TnT特异地存在于心肌中,TnT检测对AMI的诊断敏感度和特异度分别为100%、93.2%,准确度为94.7%,是一项灵敏度高、特异性强的心肌损伤血清标志物。
Serum levels of Troponin T (TnT) were measured by enzyme-linked immunosorbent assay in 25 patients with acute myocardial infarction (AMI), 33 patients with non-myocardial infarction (NMI) and 30 normal subjects. The results showed that the AMI group was 12.37 ± 7. 17ng / ml was significantly higher than the latter two groups (P <0.01); normal group 0.04 ± 0.06ng / ml, unilateral 99% confidence limits of 0.19ng / ml,> 0.2ng / Ml was positive, the positive rate of AMI group was 100%, but none of skeletal muscle injury was positive in 10 cases.The results showed that the TnT was specifically present in the myocardium, the diagnostic sensitivity and specificity of TnT for AMI were 100% 93.2%, accuracy of 94.7%, is a high sensitivity, specificity of myocardial injury serum markers.