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遗传性非息肉病性结直肠癌 (hereditarynon polyposiscolorectalcarcinoma ,HNPCC)为常染色体显性遗传性疾病 ,外显率约 5 0 % ,临床上约占大肠癌的 5 %~ 15 %。由Wathin于 1913年首先报道 ,又称Lynch综合征 ,根据?
Hereditary nonpolyposis colorectal carcinoma (HNPCC) is an autosomal dominant hereditary disorder with a penetrance of approximately 50% and clinically accounts for approximately 5% to 15% of colorectal cancer. Wathin first reported in 1913, also known as Lynch syndrome, according to?