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目的了解成都市区居民血脂水平及血脂紊乱患病率。方法随机抽取于2014年1月至2015年12月在四川大学华西医院健康体检中心进行健康体检的成都市区居民,收集每位体检者的职业、体质量、身高、血脂、血尿酸、空腹血糖检测结果,根据不同性别、年龄以及工作性质进行分组比较。结果被调查人群三酰甘油(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)的平均值分别为(1.60±1.30)mmol/L、(4.91±0.93)mmol/L、(2.70±0.75)mmol/L、(1.50±0.42)mmol/L。血脂紊乱的患病率为52.8%,男性血脂紊乱的患病率高于女性(61.75%vs 40.7%,P<0.001)。18~29岁、30~39岁、40~49岁、50~59岁和≥60岁年龄组血脂紊乱的患病率分别为27.7%、42.8%、55.5%、65.4%和61.1%。50岁以下年龄组男性血脂紊乱患病率高于女性(P<0.001),≥60岁年龄组女性血脂紊乱患病率高于男性(P<0.001)。根据职业人群分析,公务员、企事业单位、工人和其他人员血脂紊乱率分别为53.72%、53.71%、44.29%和50.02%,工人和其他人员血脂紊乱率低于公务员和企事业单位(P均<0.001)。血脂紊乱组的空腹血糖、尿酸水平高于血脂正常组(P<0.001)。结论成都地区血脂紊乱发病率较高,30岁以上男性、50岁以上女性、公务员及企事业单位工作者应作为血脂紊乱的重点筛查及防治对象。
Objective To understand the prevalence of dyslipidemia and lipid disorders in Chengdu residents. Methods The residents of Chengdu city were collected randomly from January 2014 to December 2015 in Huaxi Hospital Physical Examination Center of Sichuan University. Occupation, body weight, height, blood lipid, serum uric acid, fasting blood glucose Test results, according to different genders, age and work nature of the group comparison. Results The average values of triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) were (1.60 ± 1.30) mmol / L, 4.91 ± 0.93 mmol / L, 2.70 ± 0.75 mmol / L and 1.50 ± 0.42 mmol / L, respectively. The prevalence of dyslipidemia was 52.8%. The prevalence of dyslipidemia in males was higher than that in females (61.75% vs 40.7%, P <0.001). The prevalence of dyslipidemia was 18.7%, 42.8%, 55.5%, 65.4% and 61.1% in 18-29, 30-39, 40-49, 50-59 and 60-year-old age groups, respectively. The prevalence of dyslipidemia in men under 50 years old was higher than that in women (P <0.001). The prevalence of dyslipidemia in women ≥60 years old was higher than that in men (P <0.001). According to the analysis of occupational groups, the blood lipid disorders of civil servants, enterprises and public institutions, workers and other personnel were 53.72%, 53.71%, 44.29% and 50.02% respectively. The blood lipid disorders of workers and other staff members were lower than that of civil servants and enterprises (P < 0.001). The level of fasting blood glucose and uric acid in dyslipidemia group was higher than that in normal lipid group (P <0.001). Conclusion The prevalence of dyslipidemia in Chengdu is high. Men above 30 years old, women over 50 years old, civil servants and workers in enterprises and institutions should be the key screening and prevention targets of dyslipidemia.