Steel-mushy Al-20Sn alloy bonding was studied for the first time. The relationship model about preheat temperature of steel plate, solid fraction of Al-20Sn alloy mushy, rolling speed and interfacial shear strength of bonding plate could be established by artificial neural networks perfectly. This model could be optimized with a genetic algorithm. The optimum bonding parameters were: 505’C for preheat temperature of steel plate, 34.3% for solid fraction of Al20Sn alloy musry and 10 mm/s for rolling speed, and the largest interfacial shear strength of bonding plate was 71.2 MPa. Steel-mushy Al-20Sn alloy bonding was studied for the first time. The relationship model about preheat temperature of steel plate, solid fraction of Al-20Sn alloy mushy, rolling speed and interfacial shear strength of bonding plate could be established by artificial neural networks perfectly. This model could be optimized with a genetic algorithm. The optimum bonding parameters were: 505’C for preheat temperature of steel plate, 34.3% for solid fraction of Al20Sn alloy musry and 10 mm / s for rolling speed, and the largest interfacial The shear strength of bonding plate was 71.2 MPa.