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上期文章,我讲到了建立一个生物数据库(biobank)的国际伦理规范问题,与之相关的生物数据库应用,同样会有一些伦理问题。人类基因组测序完成之后,如何进一步利用这个庞大的数据库是基因科学家们最关注的问题,也是公众关心的问题。基因的研发即是对基因的干预,即干预人类基因的功能和演变。基因的干预有直接的和间接的方式。直接的方式就是通常所说的基因治疗、基因增强等基因工程,直接改变基因结构或组织以获得我们想要的结果。间接的方式则是通过基因药物的研发,以发挥某个基因的特殊功能,去达成
In the last issue, I talked about the issue of establishing a biobank of international ethical norms. There are also some ethical issues related to the application of biological databases. After the completion of the human genome sequencing, how to further utilize this huge database is the most important issue for genetic scientists and also a matter of public concern. Gene research and development is the intervention of genes, that interfere with the function and evolution of human genes. Gene intervention has direct and indirect ways. The direct way is the so-called gene therapy, gene enhancement and other genetic engineering, direct changes in gene structure or organization to get the results we want. Indirect way is through the development of gene drugs, in order to play a particular function of a gene, to reach