论文部分内容阅读
采用多聚酶链 限制性片段长度多态性检测技术 ,对临床上可疑的胰腺炎和胰腺癌患者 ,经收集胰液进行K ras基因第 12位密码子突变检测 ,以诊断或鉴别诊断胰腺癌。结果在 2 2份胰液标本中 ,11例胰腺炎均无K ras基因突变 ;在 11例胰腺癌病例中有 9例 (81 2 % )含K ras基因突变
Using polymerase chain-restriction fragment length polymorphism (RFLP) detection techniques, patients with clinically suspected pancreatitis and pancreatic cancer were tested for the differential diagnosis of pancreatic cancer by collecting the pancreatic juice for the 12th codon mutation in the K ras gene. Results Of the 22 pancreatic specimens, no K ras gene mutations were found in 11 cases of pancreatitis; 9 (81 2%) of them had K ras gene mutations in 11 cases of pancreatic cancer.