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尿道感染是医院获得性感染的最常见类型之一,大约占所有病例的30%,其中留置导尿管是主要危险之一。即使采用无菌封闭引流,据估计每天留置导尿管病人尿道感染率仍为5%～10%.因此,给膀胱引流的病人预防性使用抗生素仍有必要。由于顾虑产生耐药菌株,也有人反对预防性使用抗生素。作者给膀胱手术后暂时引流的病人预防性服用环丙沙星并与安慰剂对照比较。排除妊娠、肾肝功能损害、症状性尿道感染、发热或已使用抗生素的病人。选择膀胱手术后引流3～14天的病人,按双盲法
Urethral infection is one of the most common types of nosocomial infections, accounting for about 30% of all cases, with indwelling catheters being one of the major risks. Even with sterile closed drainage, it is estimated that urinary tract infections are still present in 5% to 10% of patients with catheterization every day. Therefore, prophylactic use of antibiotics in patients with bladder drainage is still necessary. Some people are opposed to the prophylactic use of antibiotics due to concern about drug-resistant strains. The authors administered ciprofloxacin prophylaxis to patients who had been temporarily drained after bladder surgery compared with placebo. Exclude pregnancy, kidney and liver dysfunction, symptoms of urinary tract infections, fever or patients who have been using antibiotics. Choose bladder surgery drainage 3 to 14 days after the patient, according to double-blind method