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并用异菸肼、氨硫脲治疗肺结核,最近又在国内重新提起。我们曾于1964—1966年间,以每日异菸肼300mg及氨硫脲150mg对复治痰菌阳性肺结核103例进行3—6月住院治疗观察,现作一分析,以供参考。103例除5例于治疗初期因药物副作用停药外,余98例完成3个月治疗者55例,痰菌阴转27例,阴转率49.1％;完成6个月治疗者43例,阴转25例,阴转率58.1％。98例计有空洞85个,治疗3个月者,51个空洞闭合9个,占17.6％;治疗6个月者,34个空洞闭合11个,占32.3％。 103例在治疗过程中出现药物副反应者27例,占26.3％。其中有肝功能障碍3例;
And with isoniazid, ammonia thiourea treatment of tuberculosis, and recently again in the country. We had in 1964-1966 years, with daily isoniazid 300mg and thiourea 150mg of sputum bacilli-positive pulmonary tuberculosis in 103 cases for 3 to 6 months in hospital treatment for an analysis for an analysis for reference. Among the 103 cases, 5 cases were discontinued due to drug side effects in the early stage of treatment, 55 cases completed 98 cases of 3 months treatment, 27 cases of sputum negative conversion and 49.1% negative conversion rate; 43 cases completed 6 months treatment, Turn 25 cases, negative conversion rate of 58.1%. Ninety-eight patients had 85 voids and were treated for 3 months. Nineteen voids were closed, accounting for 17.6%. For six months, 34 voids were closed, accounting for 32.3%. There were 27 cases of drug side-reaction in 103 cases, accounting for 26.3%. Among them, 3 cases of liver dysfunction;