论文部分内容阅读
近年来,利福平应用于临床日益增多。一般认为该药是毒性小、安全和耐受性好的抗结核药,但我科自1979年来,曾遇2例应用利福平与异菸肼联合治疗肺结核,引起严重肝功能损害,其中1例并发肝昏迷,经抢救无效死亡。为了吸取经验教训,现报告于下: 例1 马××(住院号235377),女,回族,24岁。因头痛伴恶心、呕吐近1个月,在单位卫生所对症治疗无效转来我科,门诊拟诊粟粒性肺结核并发结核性脑膜炎,于1979年12月30日收住。患者于同年3月29日
In recent years, rifampicin has been used clinically. Generally believed that the drug is toxic, safe and well-tolerated anti-TB drugs, but our department since 1979, had two cases of application of rifampicin and isoniazid combined treatment of tuberculosis, causing severe liver damage, of which 1 Cases of hepatic coma, died after rescue invalid. In order to draw lessons, the report is as follows: Example 1 Ma XX (hospital number 235377), female, Hui nationality, 24 years old. Due to headache with nausea, vomiting for nearly 1 month, the symptomatic treatment of invalid units transferred to our department, outpatient clinics miliary tuberculosis complicated by tuberculous meningitis, on December 30, 1979 admitted. Patients in the same year on March 29