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高脂血症是心血管病的独立危险因子,且可加 快慢性肾病的恶化。高脂血症在慢性肾病时常见,尤 其是在肾病综合症、长期应用糖皮质激素、腹膜透析 和血液透析,肾移植术后患者。应用HMG-COA还 原酶抑制剂常因对降低甘油三酯疗效不佳,加大剂 量后引起肝毒性而在慢性肾病高脂血症的治疗中受
Hyperlipidemia is an independent risk factor for cardiovascular disease and can exacerbate chronic kidney disease. Hyperlipidemia is common in chronic kidney disease, especially in patients with nephrotic syndrome, long-term glucocorticoid use, peritoneal dialysis, and hemodialysis and renal transplantation. HMG-COA reductase inhibitors are often used in the treatment of chronic kidney disease due to the poor curative effect of lowering triglyceride and hepatotoxicity after increasing dose