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脑、肺、支气管、胃肠道、肝、肾、子宫、血管壁、血小板等各种脏器和组织都可产生前列腺素(PG),它对于维持这些脏器和组织功能和各种疾病时临床症状的出现及病情轻重有很大关系。细胞膜中的磷脂酶使花生四烯酸转化为各种前列腺素,发挥局部激素作用。最近发现,肝病时前列腺素代谢异常可能与肝病时合并症出现和肝损害及其症状出现有关。另外,肝细胞本身也产生各种前列腺素,肝病时肝细胞内前列腺素代谢有改变。
Prostaglandins (PGs) can be produced in various organs and tissues such as brain, lung, bronchus, gastrointestinal tract, liver, kidney, uterus, blood vessel wall, platelets, etc. In order to maintain the function of these organs and tissues and various diseases The emergence of clinical symptoms and severity have a great relationship. Phospholipase in the cell membrane arachidonic acid into a variety of prostaglandins, play a role in local hormones. Recently found that liver disease abnormalities of prostaglandin metabolism may be associated with complications of liver disease and liver damage and its symptoms appear. In addition, the liver cells themselves also produce a variety of prostaglandins, hepatocellular liver cell metabolism of prostaglandins have changed.