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本文系WHO计划生育前列腺素专业组的一个综合调查报导,资料来自13个医学中心的1,001名病人的临床资料,最后分析了872例。全部病人均是妊娠第8～12周的健康初孕妇。病人分成四组:第一组225例,用含有1.0mg15-甲基-PGF_2α甲基酯的阴道栓剂治疗。第二组219例用安慰剂治疗。第三组209例,所用前列腺素及剂量与第一组相同。第四组219例用安慰剂治疗。前二组病人于吸刮前3小时插入阴道栓剂;后二组病人于吸刮前12小时插入阴道栓剂。同时给予Diphenoxylate hydroch-loride5mg以减少栓剂的腹泻发生率。全部病人的平均妊娠时间是9.6周。治疗效果:不管妊娠周数,用1.0mg15-甲基-
This article is a comprehensive survey of WHO family planning prostaglandin professional group, according to the clinical data of 1,001 patients from 13 medical centers, and the final analysis of 872 cases. All patients were pregnant during the first 8 to 12 weeks of healthy early pregnant women. The patients were divided into four groups: the first group of 225 patients treated with a pessary containing 1.0 mg of 15-methyl-PGF-2 alpha methyl ester. The second group of 219 patients were treated with placebo. The third group of 209 cases, the prostaglandin used and the same dose and the first group. The fourth group of 219 patients was treated with placebo. The first two groups of patients in the suction 3 hours before the insertion of vaginal suppository; the latter two groups of patients in the suction before 12 hours into the vaginal suppository. Simultaneously give Diphenoxylate hydroch-loride5mg to reduce the incidence of suppository diarrhea. The average pregnancy time for all patients was 9.6 weeks. Treatment effect: Regardless of the number of gestational weeks, with 1.0mg15-methyl -