青霉素过敏引起的临床症状变异很大。即刻反应包括过敏症、血管神经性水肿、荨麻疹以及某些斑丘疹;迟缓反应包括具有明确免疫学基础的血清病样反应,溶血性贫血和急性间质性肾炎等,以及其他免疫学基础不明的某些中性粒细胞减少症和由氨苄青霉素引起的斑丘疹等。即刻反应系以坛E抗体为中介而起作用,有些迟缓反应则是由她G抗体起作用。青霉素过敏发生率尚无准确数字,估计约在1%~10%之间。 Penicillin allergy caused by clinical symptoms vary greatly. Immediate reactions include allergies, angioneurotic edema, urticaria and some rash; slow reactions include serum-like reactions with a clear immunological basis, hemolytic anemia and acute interstitial nephritis, among other immunological bases Some neutropenia and ampicillin caused rash and so on. Immediate response to the altar E antibody as an intermediary and play a role, and some slow response by her G antibody. There is no exact number of penicillin allergy, it is estimated that about 1% to 10%.