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目前关于细胞凋亡相关基因与胃癌的关系,正在成为当前胃癌研究领域中的热点之一。为探讨其在胃癌的发生、发展、早期诊断、治疗及预后评价中的作用,本文将细胞凋亡相关基因P_(53)、Fas在胃癌中的表达作一简要概述。 1 细胞凋亡的概念及基因调节 细胞凋亡(apoptosis)(凋谢或凋零),该词源自古希腊语,指秋天树叶凋落。1972年英国学者Kerr等首先把这一术语引入生物学,用以描述一种不同于细
At present, the relationship between apoptosis-related genes and gastric cancer is becoming one of the hot topics in the current research field of gastric cancer. In order to explore its role in the occurrence, development, early diagnosis, treatment and prognosis of gastric cancer, this article will briefly summarize the expression of apoptosis-related genes P_(53) and Fas in gastric cancer. 1 The concept of apoptosis and gene regulation Apoptosis (withering or withering), the word originated in ancient Greek, referring to the fall of leaves in autumn. In 1972 the British scholar Kerr first introduced this term into biology to describe a