transdermal相关论文
Enhanced transdermal lymphatic drug delivery of hyaluronic acid modified transfersome for tumor meta
Tumor metastasis accounts for 90 %of cancer-associated deaths and is almost inaccessible by chemotherapy,surgical operat......
Psoriasis is an immune-mediated chronic skin disease caused by immune system mistakes and overproduction of new skin cel......
Green Electrospun Silk Fibroin Nanofibers Loaded with Cationic Ethosomes for Transdermal Drug Delive
Transdermal drug delivery system(TDDS)facilitates the controlled release of active ingredients penetrating through the s......
Effects of drug-polymer dispersions on solubility and in vitro diffusion of artemisinin across a pol
Artemisinin(ART) is a sesquiterpene lactone with an endo-peroxide bridge that is thought to be responsible for its antim......
Electroporation creates aqueous pathways by short high-voltage pulses resulting in a transient perme- abilization of str......
It is challenging for many drugs to be transported across various biological membranes. Furthermore, development of many......
Case11.Patient s conditions:An old patient had diabetes mellitus,chronicliver disease,and fast heart rate recently.Fasti......
Ethosomes-Silk Fibroin/Polyvinyl Alcohol Composite Hydrogel Transdermal Drug Delivery System : Prepa
One key of constructing ideal transdermal drug delivery system(TDDS)is enhancing the percutaneous rate of drugs without ......
Assessment of ghrelin and leptin receptor levels in postmenopausal women who received oral or transd
Objective:In postmenopausal women,an increased leptin concentration and reduced levels of ghrelin and adiponectin were o......
Insulin is a key player in the control of hyperglycemia for type 1 diabetes patients and selective individuals in patien......
Risk of venous thromboembolic disease in postmenopausal women taking oral or transdermal hormone rep
Objective: The influence of hormone replacement therapy (HRT) on hemostasis processes depends on the type of hormone,the......
目的 对芬太尼透皮贴剂治疗中重度癌症疼痛进行多中心开放性临床试验,研究该药对国人的止痛疗效及耐受性。方法 16家医院多中心临......
目的 老年癌症疼痛病人未得到足够止痛治疗的情况较常见。探讨老年癌症疼痛病人接受芬太尼透皮贴剂治疗的止痛疗效及安rrrrrrrrn全......
[Objectives]To investigate the in vitro transdermal effect of curcumin solid dispersion needles prepared with povidone K......
Transdermal drug delivery(TDD) can effectively bypass the first-pass effect. In this paper, ultrasound-facilitated TDD o......
Expressions of apoptosis-related proteins in rats with focal cerebral ischemia after Angong Niuhuang
In this study, we extracted and purified components in the Angong Niuhuang pill. Then we applied transdermal enhancers t......
Asiatic acid-pectin hydrogel matrix patch transdermal delivery system influences parasitaemia suppre
Objective: To report the influence of transdermal delivery of asiatic acid(AA) in Plasmodium berghei-infected Sprague Da......
Transdermal drug delivery (TDD) using electroporation is an attractive novel method of facilitated transport of compound......
东莨菪碱是防治晕动病(motion siekness,MS)及急性眩晕的有效药物之一。但口服或注射给药时,由于其半衰期短,需频繁给药。同时,血......
[Objective] To prepare cationic liposome gels containing paeonol, and to study its stability and cutaneous penetration k......
Continuous blood glucose monitoring is important for the diagnosis,treatment,and study of diabetes. many organizations h......
Comparison in vitro permeation of curcumin from topical gels by liquid chromatography tandem mass sp
Objective: To find a more effective method of topical transdermal delivery of curcumin. Methods: We prepared curcumin ca......
Effect of isopropyl myristate on the viscoelasticity and drug release of a drug-in-adhesive transder
The purpose of this study was to investigate the effect of isopropyl myristate(IPM), a penetration enhancer, on the visc......
Correlation between the transdermal characteristics of pseudoephedrine and amygdalin in majiepingchu
OBJECTIVE: To analyze the transdermal profile of pseudoephedrine and amygdalin in the Traditional Chinese Medicine majie......
Characteristics and pharmacokinetics of tripterygium glycosides nano-carries transdermal delivery sy
The traditional Chinese medicine tripterygium glycosides(TPG)is used clinically to treat some Rheumatism,Eczema,immunosu......
In order to solve the drawback of poor bioavailability by the oral route and infusion-related side effect for Amphoteric......
皮肤的屏障作用使大部分药物无法实现透皮给药。本文以改善难溶性大分子模型药物多烯紫杉醇(docetaxel,DTX)的经皮渗透性为主体思......
AIM: To investigate the pharmacokinetics profile of Ivermectin 1% cream after topical treatment in patients with papulop......
Pharmacokinetic and pharmacodynamic study of triptolide-loaded liposome hydrogel patch under microne
Triptolide(TP),a major active component of Tripterygium wilfordii Hook.F.(TWHF),is used to treat rheumatoid arthritis(RA......
目的探讨芬太尼透皮贴剂(transdermal fentanyl,TDF)治疗癌性疼痛(癌痛)的疗效、不良反应和对患者生活质量改善的程度。方法观察11......
Multicenter Clinical Study for Evaluation of Efficacy and Safety of Transdermal Fentanyl Matrix Patc
Objective: Although a new matrix formulation fentanyl has been used throughout the world for cancer pain management, few......
The Sleep Sleeping Patch is a new kind of external patch based on modern sleep medicine research achievements, which use......
采用水平双室扩散池,以离体鼠皮为透过屏障,考察介质和有机酸对来曲唑体外经皮透过性的影响.在肉豆蔻酸异丙酯(IPM)中加入乙醇后能......
目的:考察左旋延胡索乙素贴片体外经皮渗透,筛选贴片最佳处方。方法:采用Valia-Chien双室渗透扩散池进行体外经皮渗透实验,以大鼠......
目的研究氧化苦参碱凝胶的体外经皮渗透影响因素,并对其在大鼠体内的药动学进行研究。方法采用Valia-Chien双室扩散池,以大鼠离体......
氨基酮戊酸光动力治疗在皮肤科领域应用广泛,由于氨基酮戊酸透皮能力低,限制氨基酮戊酸光动力治疗的疗效.氨基酮戊酸衍生物,微针、......
目的 确定关节洗药内主药当归中阿魏酸的高效液相色谱法(HPLC)含量测定的最佳条件,并以阿魏酸为参考物,研究关节洗药的透皮吸收情......
制备含不同渗透促进剂的止泻凝胶膏,采用Franz扩散池考察各处方的体外透皮行为。采用HPLC法测定制品中胡椒碱含量。结果表明,当促......
目的:探讨中医定向透药疗法联合运动疗法治疗创伤后膝关节功能障碍的临床效果。方法:选择2019年11月至2020年9月萍乡市人民医院收......
为了提高大分子生物药经皮给药的治疗浓度,以多肽类生物药鲑降钙素为模型药物,研究离子导入法和化学促渗剂对鲑降钙素经皮渗透的影......
目的：观察超声靶位透药治疗颈部淋巴结结核的疗效.方法：120例颈部淋巴结结核患者随机分为超声透药组、局部注射组和对照组,每组40例.......
目的制备甲磺酸帕珠沙星凝胶,并考察其体外透皮吸收的效果。方法以卡波姆2020为基质,以离体小鼠皮肤作为透皮屏障,用改良Franz扩散......
Expert consensus of the Chinese Association for the Study of Pain on pain treatment with the transde
Chronic pain lasting more than 3 mo,or even several years can lead to disability.Treating chronic pain safely and effect......
目的:在冻融胚胎激素替代方案(HRT)中,比较给药途径不同的两种雌激素对冻融胚胎移植(FET)临床结局的影响。方法:选取2016年7月至20......
目的应用辐射化学技术对高分子材料进行辐射交联,制备经皮给药骨架型药物载体——水凝胶。方法应用45万聚居里钴60（60Co）辐射源,在辐......
目的:研究酮洛芬前体药物(酮洛芬甲酯、乙酯和异丙酯)经离体SD大鼠皮肤渗透代谢的立体选择性,为利用前体药物方法促进透皮吸收提供......
目的：研究氢溴酸高乌甲素透皮吸收性能。方法：通过考察角质层和浓度两个因素。采用HPLC和TK-20B型透皮扩散试验仪测定氢溴酸高乌甲素......
目的研制蒿甲醚贴剂，并评价其经皮吸收对感染疟原虫小鼠的杀灭及抗复燃作用。方法涂布法制备蒿甲醚贴剂，考察不同促进剂、药物的浓度......
