cyclooxygenase相关论文
Panax Notoginseng Saponin Attenuates Gastric Mucosal Epithelial Cell Injury Induced by Dual Antiplat
Objective:To elucidate the underlying mechanism of Panax notoginseng saponin(PNS)on gastric epithelial cell injury and b......
Ginkgo biloba extracts attenuate lipopolysaccharide-induced inflammatory responses in acute lung inj
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INTRODUCTION: Methyl salicylate 2-O-β-D-lactoside (MSL), whose chemical structure is similar to that of salicylic acid,......
n-Butanol extract of Chinese toon fruit ameliorated focal brain ischemic insult in rats via inhibiti
Aim: To evaluate the neuroprotective efficacy of Chinese toon on cerebral ischemic reperfusion model of rats and explore......
Vascular Reactivity Screen of Chinese Medicine Danhong Injection Identifies Danshensu as a NO-Indepe
Danhong injection (DHI) is the most prescribed injection form of Chinese medicine for the treatment of cardiovascular di......
0.引言环氧合酶(cyclooxygenase,cox)是花生四烯酸生物合成前列腺素的限速酶。包括cox-1和cox-2两种亚型,其中cox-2的过度表达与胃......
Non-steroidal anti-inflammatory drugs(NSAIDs)inhibit prostaglandin(PG)formation by targeting cyclooxygenase(COX)1 and 2.......
The Effect of Nimesulide on the Expression of NF-κB,Bcl-2 and Bax in the Human Gastric Cancer SGC-79
OBJECTIVE To investigate whether nimesulide can suppress tumor growth and induce apoptosis in SGC-7901 gastric cancer ce......
Anti-hepatoma activity and mechanism of ursolic acid and its derivatives isolated from Aralia decais
AIM:To investigate the anti-tumor activity of ursolic acid(UA)and its derivatives isolated from Aralia decaisneanaon he......
坏死性小肠结肠炎(necrotizing enterocolitis,NEC)是一种由于对菌群的过度炎症反应而导致肠坏死的新生儿疾病,是导致早产儿死亡的......
Synthesis and biological evaluation of 3-amino-2-pyrones as selective cyclooxygenase-1(COX-1) inhibi
A group of 3-amino-2-pyrones were synthesized and their biological activities were evaluated for inhibiting cyclooxygena......
目的:探讨缺氧后新生鼠脑内阿米巴样小胶质细胞(amoeboid microglial cell,AMC)环氧合酶(cyclooxygenase-2,COX-2)的表达。方法:将......
目的 研究膜相关前列腺素E2 合成酶 (membrane associatedprostagladinE2 synthase ,mPGES)与类风湿关节炎的关系。方法 用反转......
Objective: To evaluate cyclooxygenase-2 (COX-2) expression induced by insulin in cultured rat vascular muscle smooth cel......
Effects of aspirin on atherosclerosis and the cyclooxygenase-2 expression in atherosclerotic rabbits
Background Atherosclerosis is a complex vascular inflammatory disease. Aspirin is a mainstay in the prevention of vascul......
Mechanism research and effect of ulinastatin in the brain tissue injury of acute hydrogen sulfide in
Objective To observe the effect of Ulinastatin(UTI)in the dynamic changes of aquaporin 4(AQP4)and cyclooxygenase-2(COX-2......
Role of prostacyclin receptors in the vasoconstrictor response evoked by cyclooxygenase-1 or-2 media
AIM:In the vascular wall,the metabolism of arachidonic acid(AA)catalyzed via cyclooxygenase(COX)leads to the formation o......
Effect of interleukin-6 / signal transducer and activator of transcription 3 pathway on cyclooxygena
Objective To investigate the relationship between the interleukin-6(IL-6)/signal transducer and activator of transcripti......
AIM:To clarify the significance of cyclooxygenase-2(COX-2)expression in human primary hepatocellular carcinoma(HCC)and ......
AIM:To evaluate the expression of cyclooxygenase(COX-2)and the relationship with tumor angiogenesis andadvancement in g......
AIM:Cyclooxygenase-2 is involved in a variety of importantcellular functions,including cell growth and differentiation,......
AIM:To observe the expression of cyclooxygenase-2(COX-2)and to investigate the association between COX-2expression and ......
Role of COX-2 in carcinogenesis of colorectal cancer and its relationship with tumor biological char
AIM:Recent clinical epidemiological studies havedemonstrated the preventive effect of non-steroidal anti-inflammatory d......
AIM:To study the expression of cyclooxygenase-2(COX-2)gene in gastric cancer and the relationship between COX-2expressi......
AIM:To investigate the influence of peroxisome proliferator-activated receptor γ(PPARγ)ligand,15-deoxy-△12,14-prosta......
AIM:To investigate the role of cyclooxygenase-2(COX-2)and vascular endothelial growth factor (VEGF) in thedevelopment o......
Celecoxib inhibits proliferation and induces apoptosis via prostaglandin E_2 pathway in human cholan
AIM:To evaluate the roles and mechanisms of celecoxib ininducing proliferation inhibition and apoptosis of humancholang......
AIM:To investigate whether troglitazone (TGZ),theperoxisome proliferator-activated receptor (PPAR) gammaligand,can indu......
目的 探讨环氧化酶 - 2 (COX - 2 )表达与膀胱癌生物学行为的关系及其意义。方法 采用免疫组化SABC法检测 5 4例膀胱癌、2 9例癌......
目的研究环氧合酶-2(cyclooxygenase-2,COX-2)在肝癌细胞中的表达. 方法采用免疫细胞化学,RT-PCR方法研究人肝癌细胞系中COX-2的表......
AIM:Cyclooxygenase(COX)-2 is over expressed ingastrointestinal neoplasm.Helicobacter pylori(H pylon)infection is causal......
AIM:To determine whether cyclooxygenase-2(COX-2)wasexpressed in human esophageal squamous cell carcinoma.METHODS:Quanti......
AIM:Cyclooxygenase-2 (COX-2) is one of the rate-limitingenzymes in metabolism of arachidonic acid,and COX-2inhibitors d......
AIM: To investigate effects of cyclooxygenase 2 (COX-2) inhibitors on nasopharyngeal carcinoma (NPC) cells and on angio......
目的 :研究肾癌组织中环氧化酶 2 (COX 2 )蛋白的表达 ,探讨COX 2表达与肾癌可能的相关性。方法 :应用免疫组织化学S P法 ,对 4 6......
AIM:The protective effects of sodium butyrate and NSAIDs(especially the highly selective COX-2 inhibitors)haveattracted......
AIM: To clarify the clinicopathologic significance of COX-2 expression in human colorectal cancer. METHODS: A total of 1......
AIM: To investigate the relation between the expression of cyclooxygenase-2 (COX-2) and liver cancer, to construct the r......
AIM: To determine the correlation between methylation status of 5’ CpG island of cyclooxygenase-2 (COX-2) gene and prot......
AIM: To investigate the expression of cyclooxygenase-2 (COX-2) in gastric cancer and its relation with the liver metasta......
Decline in fertility in bovines is attributed to various reproductive problems viz. anoestrus, repeat breeding, abortion......
[目的]探讨持续动态压应力环境对实验性骨折愈合的影响及环氧化酶-2(cyclooxygenase,COX-2)、前列腺素E2(prostaglandin E2,PGE2)......
Cyclooxygenase-2 promotes angiogenesis by increasing vascular endothelial growth factor and predicts
AIM: To investigate the relationships between theexpression of cydooxygenase-2 (COX-2), vascular endothelial growth fact......
目的 观察5-脂氧合酶拮抗剂MK886、环氧化酶2拮抗剂Celeeoxib干预SW1990细胞后对细胞增殖及血管内皮生长因子(VEGF)mRNA表达的影响......
Objective: To evaluate the antiarthritic activity of Ajuga bracteosa using albino rats. Methods:The antiarthritic activi......
AIM: To invest igate the protect ive effects of electroacupuncture (EA) pretreatment on acetylsalicylic acid (ASA)-induc......
Effects of different concentrations of celecoxib on proliferation and cell cycle of SH-SY-5Y cells a
BACKGROUND:Highly selective cyclooxygenase-2(COX-2)inhibitors have recently been approved for the treatment of colon can......
目的 探讨环氧化酶-2(COX-2)及微血管密度(MVD)与膀胱移行细胞癌生物学行为的关系及其临床意义.方法 采用免疫组化S-P法对103例膀......
