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Galactosylated chitosan/5-fluorouracil nanoparticles inhibit mouse hepatic cancer growth and its sid
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Macrophage membrane-mediated targeted drug delivery for treatment of spinal cord injury regardless o
Targeted delivery of therapeutics for spinal cord injury(SCI)has been a long-term challenge due to the complexity of the......
Molecular-targeted therapy toward precision medicine for gastrointestinal caner:Current progress and
Gastrointestinal(GI)cancer remains the deadliest cancer in the world.The current standard treatment for GI cancer focuse......
The Phytophthora effector Avh241 interacts with host NDR1-like proteins to manipulate plant immunity
Plant pathogens rely on effector proteins to suppress host innate immune responses and facilitate colonization.Although ......
Hypertriglyceridaemia(HTG) is a risk factor for cardiovascular disease(CVD) in type 2 diabetes and is caused by the inte......
Patients on oral anticoagulation(OAC),who are referred for coronary artery stenting account for about 5% of the whole po......
Atopic dermatitis(AD) is a chronic inflammatory skin disorder which can precede asthma and allergic rhinitis in a diseas......
Purification and characterization of Moschatin, a novel type Ⅰ ribosomeinactivating protein from the
A novel ribosome-inactivating protein designated Moschatin from the mature seeds of pumpkin (Cucurbita moschata) has be......
AIM:To study the effect of siRNA expressed from DNA vectoron HBV replication.METHODS:Human U6 promoter was amplified fr......
上皮细胞间质转化(EMT)是指上皮细胞在一定条件下获得间质细胞表型的过程.研究表明,EMT是结直肠癌发生、发展中的关键步骤之一.肿......
目的 探讨老年原发性高血压合并糖尿病患者血压昼夜节律改变、血压变异性及其与靶器官损害的关系.方法 根据合并糖尿病情况,将老年......
Aim: Primary tumors can be divided into oncogene-addicted (e.g., lung) and non-oncogene addicted (e.g., breast). Only th......
Some growth factor receptors, such as insulin like growth factor Ⅰ and Ⅱ receptor (IGF Ⅰ R, IGF Ⅱ R) and epidermal ......
An Awareness-Adoption Matrix for Strategic Decision Making in Agricultural Development Projects: A C
Significant achievements have been made in generating sustainable agricultural technologies in developing countries. Usu......
In this study, novel liver targeted doxorubicin (DOX) loaded alginate (ALG) nanoparticles were prepared by CaCl2 crossli......
Gene therapy is a potentially effective treatment for retinal degenerative diseases.Clustered regularly interspaced shor......
Key advances in multifunctional magnetic nanoparticles(MNPs) for magnetic resonance(MR) image-guided photothermal therap......
Neuroprotective mechanisms and translational potential of therapeutic hypothermia in the treatment o
Stroke is a leading cause of disability and death,yet effective treatments for acute stroke has been very limited.Thus f......
AIM: To study the effect of inhibited E-cadherin expression on invasion of cancer cells. METHODS: We designed the nucleo......
Exploring Mechanisms of Panax notoginseng Saponins in Treating Coronary Heart Disease by Integrating
Objective: To investigate the mechanisms of Panax notoginseng saponins(PNS) in treating coronary heart disease(CHD) by i......
The link of hedgehog (Hh) signaling activation to human cancer and synthesis of a variety of Hh signaling inhibitors rai......
To improve the therapeutic effect of rhaponticin(RHA),a folate receptor(FR) targeted RHA prodrug was designed and regios......
Screening of differentially expressed genes related to differentiation and proliferation by gene exp
BACKGROUND: The detection of differential gene expression in brain is possible by cDNA microarray technology, and the sc......
Lymph node metastasis is the hallmark of colon cancer progression,and is considered one of the most important prognostic......
Target binding and residence:a new determinant of DNA double-strand break repair pathway choice in C
The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) is widely used......
Pancreatic cancer is one of the most devastating solid tumors,and it remains one of the most difficult to treat.The trea......
Nucleic acid aptamers, which are generated by a novel technique called SELEX(systematic evolution of ligands by exponent......
Abnormal protein expression or activities are associated with many diseases,especial ly cancer.Therefore,down-regulating......
Cancer stem cells(CSCs) constitute a small proportion of the cancer cells that have self-renewal capacity and tumor-init......
Purpose:As smartphones become ubiquitous,it is important to understand emerging information behavior as a result of wide......
The annual meeting of the Heart Failure Association of ESC in Lisbon,in June 2005,was exceptionally successful.There we......
Target detection is always an important application in hyperspectral image processing field. In this paper, a spectral-s......
To a student of English, reading is one of the four basic skills. And his ultimate goal in reading English is to be able......
介绍一种新的差分GPS方法,既位置差分法.在目标用户监测系统中,利用这种方法,用户可以简单地使用GPS OEM接收机将位置数据发送到监......
ras-丝裂原活化蛋白质激酶通路细胞信号转导网调节细胞的分化、细胞骨架的构建、蛋白质的转运等许多生理过程.近年来在肿瘤治疗中......
肿瘤的侵袭和转移是决定疾病转归的关键因素,胃癌侵袭转移过程中影响因素包括生长因子及其受体、细胞黏附分子、基质降解酶和细胞......
PI3K/Akt信号通路作为细胞内重要信号转导通路之一,通过影响下游多种效应分子的活化状态,在细胞内发挥抑制凋亡、促进增殖的关键作......
A single-particle microbeam facility has been constructed at the Key Laboratory of Ion Beam Bioengineering (LIBB), Chine......
中空介孔二氧化硅具有中空腔结构、低密度、大比表面积、良好的生物相容性和稳定性以及表面易修饰等理化特性,在生物医学领域中受......
西部地区农村贫困问题的研究有助于推动脱贫攻坚和乡村振兴战略的有效实施。文章基于2018年中国家庭追踪调查(CFPS)的数据,运用Pro......
随着我国的汽车保有量速增长,自动驾驶的技术开始兴起,而交通标志检测是自动驾驶当中的一个重要的构成部分。交通标志的检测往往会......
目的:分析造成慢性鼻窦炎患者睡眠障碍的相关影响因素及护理干预措施。方法:选取2018年1月至2020年1月来安徽省蚌埠市第一人民医院......
针对图像检测识别和目标跟踪技术中存在的抗遮挡性弱、无法应对目标丢失、对目标多尺度变化适应不了等问题,设计开发了基于Jetson ......
本文分析了同济医科大学附属协和医院伽玛刀治疗研究中心二年多来运用伽玛刀治疗９例眼内肿瘤的有关资料。......
激光水推进技术是一种新概念的推进技术，其原理是以水作为推进工质，通过强激光辐照后水的爆炸、反喷进行驱动，具有很高的冲量耦合系数......
为了解决靶场测试中对于双管齐射武器飞行矢量和着靶坐标的测量问题,提高测试精度,介绍了一种基于多幕面装置的非接触测试方法。文......
目的：比较4种靶／非靶比值（target．to．nontargetratio，T／NT）的诊断价值，选择更佳评估甲状腺相关性眼病（thyroid associated ophthalmopathy，TAO......
论述了钢铁工业与技术创新的关系,提出了我国新一代钢铁制造流程的优化问题,指明了钢铁工业技术创新的方向和目标,并强调要用新型......
