neuroinflammation相关论文
Advances in the knowledge on the role of apoptosis repressor with caspase recruitment domain in hemo
Theapoptosisrepressorwithcaspaserecruitmentdomain(ARC)playsacriticalroleinextrinsicapoptosisinitiationviadeathreceptorli......
抑郁症是一种以情绪低落为主要表现的常见精神障碍，其病理生理机制复杂且药物治疗效果欠佳。丰富环境(environmental enrichment，EE)......
Parkinson\'s disease, the most common movement disorder, has a strong neuroinflammatory aspect. This is evident by inc......
肝性脑病(Hepatic encephalopathy，HE)是终末期肝病的主要并发症，可造成认知障碍、注意力减退和运动功能障碍，重者昏迷、死亡。HE发病......
目的 研究参远苷对脂多糖诱导的BV2小胶质细胞炎症反应的治疗作用.方法 采用细胞增殖-毒性检测(CCK-8)法评价参远苷对BV2小胶质细......
HACE1 negatively regulates neuroinflammation through ubiquitylating and degrading Rac1 in Parkinson&
Neuroinflammation plays an important role in neurodegenerative diseases,such as Parkinson\'s disease(PD)and Alzheimer......
Genetic variation in apolipoprotein E(APOE)influences Alzheimer\'s disease(AD)risk.APOE e4 alleles are the strongest g......
Minocycline Activates the Nucleus of the Solitary Tract- Associated Network to Alleviate Lipopolysac
Objective To examine the neuroanatomical substrates underlying the effects of minocycline in alleviating lipopolysacchar......
小胶质细胞控制着中枢神经系统主要的免疫功能,在各种精神疾病中发挥重要作用.某些信号通路的激活引发的神经炎症与抑郁症的发生有......
Parkinson\'s disease (PD),the second most common neurodegenerative disease,is clinically charac-terized by both motor ......
Dlg1 Knockout Inhibits Microglial Activation and Alleviates Lipopolysaccharide-Induced Depression-Li
Microglia-mediated neuroinflammation is widely perceived as a contributor to numerous neurological diseases and mental d......
Microglia activation, classification and microglia-mediated neuroinflammatory modulators in subarach
Subarachnoid hemorrhage is a devastating disease with significant mortality and morbidity, despite advances in treating ......
The mechanism behind activation of the Nod-like receptor family protein 3 inflammasome in Parkinson&
Previous studies have shown that the ATP-P2X4 receptor signaling pathway mediates the activation of the Nod-like recepto......
Exposure to explosive shockwave often leads to blast-induced traumatic brain injury in military and civilian populations......
The discovery that new neurons are produced in some regions of the adult mammalianbrain is a paradigm-shift in neuroscie......
The phenotypic convergence between microglia and rperipheral macrophages during development and rneu
Microglia, the tissue resident macrophages of the brain, are increasingly recognized askey players for central nervous s......
A major feature of neurodegeneration is disruption of central nervous system homeostasis, during which microglia play di......
Astrocytes are integral components of the central nervous system, where they are involved in numerous functions critical......
Argon reduces microglial activation and inflammatory cytokine expression in retinal ischemia/reperfu
We previously found that argon exerts its neuroprotective effect in part by inhibition of the toll-like receptors (TLR) ......
Extract of Fructus Schisandrae chinensis Inhibits Neuroinflammation Mediator Production from Microgl
Objective:To investigate the anti-neuroinflammation effect of extract of Fructus Schisandrae chinensis (EFSC) on lipopol......
Brazilein inhibits neuronal inflammation induced by cerebral ischemia and oxygen-glucose deprivation
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Protosappanin A exerts anti-neuroinflammatory effect by inhibiting JAK2-STAT3 pathway in lipopolysac
Microglial activation and resultant neuroinflammatory response are implicated in various brain diseases including Alzhei......
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Increased EZH2 Levels in Anterior Cingulate Cortex Microglia Aggravate Neuropathic Pain by Inhibitin
After brachial plexus avulsion (BPA),microglia induce inflammation,initiating and maintaining neuropathic pain.EZH2 (enh......
Radio Electric Asymmetric Conveyer Technology Modulates Neuroinflammation in a Mouse Model of Neurod
In this study,the effects of Radio Electric Asymmetric Conveyer (REAC),a non-invasive physical treatment,on neuroinflamm......
Neural stem cell transplantation decreases neuroinflammation in a transgenic mouse model of Alzheime
Inammatory mediators. Our results showed that in NSC-injected APP/PS1 mice, activation of GFAP, Iba-1, TLR4 and TLR4 pat......
The knockdown of Regnase-1 in microglia exacerbates inflammation and neuronal injury mediated by HMG
Background: Neuroinflammtion plays a key role in pathologic processes of a wide number of central nervous system(CNS)dis......
Ginkgo Biloba extract(EGb 761)attenuates lipopolysaccharide-induced inflammatory responses in N9 mic
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Objective Brain inflammation plays an important role in the pathophysiology of many psychiatric and neurological disease......
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Minocycline reduces neuroinflammation but does not ameliorate neuron loss in a mouse model of neurod
Minocycline is a broad-spectrum tetracycline antibiotic.A number of preclinical studies have shown that minocycline exhi......
Objective Cathepsin C(dipeptidyl peptidase I,DPPI)is a lysosomal cysteine proteinase,which belongs to papain superfamily......
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Introduction Microglial activation contributes to neuroinflammation and neuronal damages in neurodegenerative disorders ......
Objective Neuroinflammation after cerebral ischemia/reperfusion(I/R)is characterized by the accumulation of inflammatory......
Sphingosine kinases(Sphks) are the rate-limiting kinases in the generation ofsphingosine-1-phosphate,which is a well-est......
Background: Accumulating evidence suggests that neuroinflammation plays an important role in the progression of Parkinso......
Trans-Cinnamaldehyde Improves Memory Impairment by Blocking Microglial Activation in Mice Challenged
Microglia activation and neuroinflammation are critically involved in pathogenesis of neurodegenerative disorders.Patien......
Protective Effects of Ginsenoside Rg1 on LPS-induced Astrocyte Activation in cultured rat primary as
Ginsenoside Rg1,an active component of ginseng,has been shown to attenuate LPS-induced inflammatory responses in RAW267.......
The influence of maternal stress-induced dysregulation of neuroinflammatory responses on neurodevelo
Objective Clinical investigation indicates that prenatal stress could result in adverse neuroanatomical,biological and b......
Targeting cPLA2 inhibition to reduce lysophosphatidylcholine (LPC) production induced by Cdk5/p25: A
Aim: The deregulation of cyclin-dependent kinase 5 (Cdk5) by p25 and neuroinflammation has been linked to the pathogenes......
Cerebroprotection by hesperetin is associated with restoration of tryptophan metabolic enzyme system
Aim: The tryptophan metabolic enzyme systems of indoleamine 2,3-dioxygenase (IDO) and tryptophanyl-tRNA synthetase (TrpR......
The inhibitory effect of methyl salicylate 2-O-β-D-Iactoeide (MSL) on inflammation in LPS-induced mi
Aim: To study the inhibitory effect of methyl salicylate 2-O-β-D-lactoside (MSL) on LPS-induced BV-2 cell.Methods: BV-2......
Traditional Chinese medicine with reinforcing kidney activity ameliorate experimental autoimmune enc
Aim: The present study was designed to determine whether traditional Chinese medicine with reinforcing kidney activity s......
Trans-Cinnamaldehyde Inhibits Microglial Activation and Improves Neuronal Survival against Neuroinfl
Background:Microglial activation contributes to neuroinflammation and neuronal damages in neurodegenerative disorders in......
Alcohol abuse and addiction are huge obsessions to people invoking severe social problem.Previous Studies show that trau......
Aim Brain inflammation plays an important role in the pathophysiology of many psychiatric and neurological diseases.Angi......
Tetrahydroxystilbene glucoside protects LPS-induced dopaminergic neurodegeneration via the inhibitio
Aim: Parkinson disease (PD) is one of the most common neurodegenerative diseases characterized by progressive dopaminerg......
Activated microglia are implicated in cognitive deficits,brain damage as well as recovery after inte
Objective Microglia are the primary immune effector cells in the brain and play a pivotal role in the neuroinflammatory ......
