HACE1相关论文
HACE1 negatively regulates neuroinflammation through ubiquitylating and degrading Rac1 in Parkinson&
Neuroinflammation plays an important role in neurodegenerative diseases,such as Parkinson\'s disease(PD)and Alzheimer......
目的:探讨富马酸二甲酯(DMF)对急性T淋巴细胞白血病的影响及潜在的作用机制,为临床治疗急性T淋巴细胞白血病提供实验基础和理论依......
目的：HACE1是位于6q21染色体上的潜在肿瘤抑制基因，通过介导细胞自噬、Rac1的泛素化等多种作用机制参与肿瘤细胞的生长和凋亡调控.HA......
Ubiquitylation of Autophagy Receptor Optineurin by HACE1 Activates Selective Autophagy for Tumor Sup
In selective autophagy, receptors are central for cargo selection and delivery.However, it remains yet unclear whether a......
.An increasing body of evidence suggested that downregulation or deletion of HECT domain and ankyrin repeat containing E......
Ubiquitylation of Autophagy Receptor Optineurin byHACE1,a E3 ubiquitin ligase,Activates Selective Au
In selective autophagy,receptors are central for cargo selection and delivery.However,itremains yet unclear whether ......
结肠癌(Colon cancer,CRC)如今成为危害人类健康的严重疾病。由于结肠癌具有不同的分子表型和极高的死亡率。因此,急需确定结肠癌......
结外鼻型NK/T细胞淋巴瘤(NKTCL)是由自然杀伤细胞或较少见的T细胞中细胞毒性淋巴细胞增生紊乱引起的一种恶性肿瘤,与EB病毒感染有......
肝细胞肝癌(Hepatocellular carcinoma,HCC)(以下简称肝癌)是目前世界上最常见的恶性肿瘤之一,在全球,肝癌的发病率不断攀升。流行......
HACE1不仅是一种重要的肿瘤抑制基因,通过介导细胞自噬、Rac1的泛素化等多种作用机制发挥重要的肿瘤抑制作用,而且还涉及到众多的......
