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  5. Cerebroprotection by hesperetin is associated with restoration of tryptophan metabolic enzyme system

Cerebroprotection by hesperetin is associated with restoration of tryptophan metabolic enzyme system

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：ruyang0828
【摘 要】
：
Aim: The tryptophan metabolic enzyme systems of indoleamine 2,3-dioxygenase (IDO) and tryptophanyl-tRNA synthetase (TrpRS), which are involved in L-tryptophan catabolism and its use in protein synthes
【作 者】
：
So Jung KIM So Yeon KIM Yuli FANG Won Suk LEE 
【机 构】
：
Department of Pharmacology,and MRCITR, Pusan National University School of Medicine, Yangsan, Gyeong
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
cerebral ischemia neuroinflammation neuroprotection 
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Aim: The tryptophan metabolic enzyme systems of indoleamine 2,3-dioxygenase (IDO) and tryptophanyl-tRNA synthetase (TrpRS), which are involved in L-tryptophan catabolism and its use in protein synthesis, respectively, are associated with the neuroinflammation and immune response to acute cerebral ischemia.Hesperetin, a citrus flavanone, is known to help prevent tissue damage from oxidative stress in the brain.
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