midkine相关论文
目的:MDK（Midkine）已经被认为是诊断肝细胞癌（Hepatocellular carcinoma,HCC）的最有前景的标志物之一。本研究通过比较MDK和甲胎蛋白（Al......
目的:探讨血清midkine(MK)、高迁移率族蛋白B1(HMGB1)在甲状腺癌手术前后变化及其诊断学价值.方法:选取我院甲乳外科确诊的80例甲......
一、大鼠气道平滑肌细胞中Midkine的表达目的明确midkine在大鼠气道平滑肌细胞（Airway smooth muscle cells,ASMC）中的表达方法本研......
Long noncoding RNAs (lncRNAs) participate in many pathophysiological processes after traumatic brain injury by mediating......
Midkine as a potential diagnostic marker in epithelial ovarian cancer for cisplatin/paclitaxel combi
Midkine (MK),known as a novel tumor biomarker,has been elevated in the serum of patients with epithelial ovarian cancer ......
Midkine（MK）有多重生物学功能，对肿瘤的诊治具有重要作用。MK在不同的肿瘤中高度表达，促进癌细胞增殖、迁移和新生血管形成。近年来的......
目的Midkine(MK)和核因子κB(NF-κB)在肿瘤发生过程中起着重要的作用，均被认为是新的恶性肿瘤生物标志物。本研究旨在探讨免疫组化......
目的:观察中期因子(Midkine)、循环肿瘤细胞(CTCs)在肝细胞癌患者外周血中的表达水平,并研究它们与肝癌临床病理参数之间的关系.方......
中期因子（midkine，MK）是一种肝素结合生长因子。与炎性疾病、肿瘤、神经病变性疾病及AIDS的发生有着重要的关系。MK在多种实体肿瘤中......
中期因子(midkine,MK)作为肝素结合因子家族的成员,在胚胎期广泛分布,出生后局限于特定部位,在神经生长、血管生成、肿瘤发生、组......
目的:研究中期因子(midkine,MK)蛋白在食管癌中的表达情况,并探讨MK与其生物学行为的关系.方法:采用免疫组织化学S-P法,检测45例食......
目的 中期因子(MK)是一种新的肝素结合生长因子，其多种生物学活性与癌有关。近年来国外研究报道，多种人类实体肿瘤存在中期因子......
目的 构建谷胱甘肽-S-转移酶(GST)和中期因子(MK)融合蛋白的原核表达质粒,并表达和纯化蛋白,制备多克隆抗体.方法 通过RT-PCR技术......
目的分析血液中相关生物活性因子水平与糖尿病性视网膜病变(DR)严重程度的相关性。方法采用前瞻性研究法，收集2016年6月至2018年12......
Enhanced therapeutic effects of combined chemotherapeutic drugs and midkine antisense oligonucleotid
AIM: To evaluate the effect of combined antisense oligonucleotides targeting midkine (MK-AS) and chemotherapeutic drugs ......
Over-expressed and truncated midkines promote proliferation of BGC823 cells in vitro and tumor growt
AIM: To determine whether midkine (MK) and its truncated form (tMK) contribute to gastric tumorigenesis using in vitro a......
In vitro and in vivo suppression of hepatocellular carcinoma growth by midkine-antisense oligonucleo
AIM: To synthesize antisense oligonucleotides (ASODNs) of midkine (MK), package the ASODNs with nanoparticles, and to in......
生长因子是控制细胞分裂和增殖的重要因素,与肿瘤的发生和发展密切相关.Midkine家族是生长因子家族的新成员,研究表明其在肿瘤的发......
H.sinensis mycelium inhibits epithelial-mesenchymal transition by inactivating the midkine pathway i
The medical fungus Hirsutella sinensis has been used as a Chinese folk health supplement because of its immunomodulatory......
Serum midkine levels for the diagnosis and assessment of response to interventional therapy in patie
Objective:To explore the clinical significance of serum midkine(MDK) levels for the diagnosis of hepatocellular carcinom......
Construction of a fusion protein expression vector MK-EGFP and its subcellular localization in diffe
AIM: To construct an expression plasmid encoding hu-man wild-type midkine (MK) and enhanced green fluo-rescence protein ......
Antisense oligonucleotides targeting midkine inhibit tumor growth in an in situ human hepatocellular
阜阳市局 ￡4a 局长——_MINtkMMtgj’＃lnH＄B——q.M——D收束志不他只邀狲位J则【科校为先导推动地租工作.B为广为戳民U用凶盼引眯B.......
Enhanced therapeutic effects of combined chemotherapeutic drugs and midkine antisense oligonucleotid
AIM: To evaluate the effect of combined antisense oligonucleotides targeting midkine (MK-AS) and chemotherapeutic drugs ......
AIM: To evaluate the effect of antisense oligonucleotide targeting midkine (MK-AS) on angiogenesis in chick chorioallant......
Midkine (MK), a heparin-binding growth factor, can regulate cell growth, survival and differentiation. MK is expressed a......
Midkine is a heparin-binding growth factor, which plays important roles in the regulation of cell growth and differentia......
Antisense oligonucleotides targeting midkine induced apoptosis and increased chemosensitivity in hep
Aim:Overexpression of midkine(MK)has been observed in many malignancies.This aim of this study is to screen for suitabl......
BACKGROUND: Several studies have shown that midkine directly participates in tumor cell growth and invasion, as well as ......
AIM: To invesgate the ultrastructural location of midkine (MK) in nucleolus and function corresponding to its location.M......
Over-expressed and truncated midkines promote proliferation of BGC823 cells in vitro and tumor growt
AIM: To determine whether midkine (MK ) and its truncated form (tMK) contribute to gastric tumorigenesis using in vitro ......
Correlation and Significance of Midkine and Estrogen Receptor Beta Protein Expression in Non-Small C
OBJECTIVE Midkine (MK),a new member of the heparin-binding growth factor family,was found recently to have a highexpres......
Midkine(MK) is a heparin-binding growth factor with its gene first identified in embryonal carcinoma cells at early stag......
In vitro and in vivo suppression of hepatocellular carcinoma growth by midkine-antisense oligonucleo
AIM:To synthesize antisense oligonucleotides (ASODNs) of midkine (MK), package the ASODNs with nanoparticles, and to inh......
Objective:To investigate the silencing effects of recombinant adenovirus Ad-shRNA-MK on midkine(MK) gene in pancreatic c......
Objective:Midkine(MK),a new member of the heparin-binding growth factor family,has been found recently to have a high ex......
目的:研究人脑胶质瘤中中期因子蛋白(MK)和增殖细胞核抗原(PCNA)的表达,探讨两者在胶质瘤的侵袭和恶性进展中的作用。方法:应用免......
糖胺聚糖(glycosaminoglycan,GAG)是一类含有糖醛酸和氨基糖残基的重要生物大分子。在细胞表面和细胞外基质中存在着一些高亲和力......
目的研究结直肠癌中中期因子(midkine,MK)和VEGF的表达与临床病理学特征关系。方法应用免疫组织化学方法检测49例直肠癌组织以及20......
中期因子(midkine,MK)是肝素结合性生长因子家族中新发现的一类成员,是一种分泌型肝素结合生长因子,在小鼠妊娠中期广泛表达,出生......
AIM:To investigate midkine(MK)and syndecan-3protein expression in pancreatic cancer by immunohistochemistry,and to analy......
中期因子(midkine,MK)是肝素结合性生长因子家族中新发现的一类成员,是一种分泌型肝素结合生长因子,在小鼠妊娠中期广泛表达,出生......
中期因子(midkine,MK)是肝素结合性生长因子家族中新发现的一类成员,是一种分泌型肝素结合生长因子,在小鼠妊娠中期广泛表达,出生......
目的:观察中期因子(midkine,MK)基因对人乳腺癌MDA-MB-231细胞增殖、迁移、黏附和侵袭能力的影响。方法:实时荧光定量PCR和蛋白质......
该文第一部分:Midkine的功能与结构的研究进展.第二部分:鼠MK基因的克隆、表达及MK蛋白质的分离纯化及活性测定.第三部分:Midkine......
