deoxy相关论文
Small-animal PET demonstrates brain metabolic change after using bevacizumab in a rat model of cereb
To evaluate the effect of bevacizumab on cerebral ischemia,we used 2-deoxy-2-~(18)F-fluoro-D-glucose(~(18)F-FDG)small-an......
The molecular hydrogen complex of osmium,[trans-en2Os(η-H2)]2+(en,entlylendediamine) is a new 1H NMR recognition probe ......
本研究描述了利用2,3-环氧吡喃糖硫苷作为糖基化试剂制备2-脱氧吡喃糖苷的方法。在Cu(OTf)_2的介导下,2,3-环氧吡喃糖硫苷与糖基受......
An easy route to exotic 9-epimers of 9-amino-(9-deoxy) cinchona alkaloids with(8S,9R) and(8R,9S)-con
Four exotic chiral organocatalysts,9-amino-(9-deoxy) cinchona alkaloids with(8S,9R) and(8R,9S)-configurations,were conve......
In order to develop a novel kidney-targeted drug delivery system,a small molecular carrier(2-deoxy-2-aminodiglucose) was......
A naturally occurring nucleoside disulfide,9-(5’-deoxy-5’-thio-β-D-xylofuranosyl)adenine disulfide,was first synthesi......
Design,synthesis and biological activity of cyclohexane-bearing C-glucoside derivatives as SGLT2 inh
Seven cyclohexane-bearing C-glucoside derivatives(7,9,12,13 and 17-19) were designed and synthesized as SGLT2 inhibitors......
2-Deoxy glycosides are widely presented in natural products and clinical reagents.The presence of 2-deoxy glycosides is ......
An intramolecular organocatalytic enantioselective aza-Michael reaction of carbamates, sulfonamides and acetamides to a,......
Comparisons between glucose analogue 2-deoxy-2-(~(18)F)fluoro-D-glucose and ~(18)F-sodium fluoride p
AIM: To compare 2-deoxy-2-(~(18)F)fluoro-D-glucose(~(18)FFDG) and ~(18)F-sodium(~(18)F-NaF) positron emission tomography......
Two new triterpenoid saponins,cincholic acid-3- O - β - D -xylopyranoside,28- O - β - D -glucopyranosyl ester (1),quin......
A peak/ratio in pyrene-fluorescence spectrum was employed to measure the polarity of micro-environment of chitosan adsor......
A series of 2’-purine and pyrimidine derivatives of 1’ ,4’-anhy-dro-2’-deoxy-D-arabitol (1) and 1’, 4’-anhydro-2......
Molecular recognition studies on supramolecular systems (XXIV)——Conformations and complexation abili
Circular dichroism spectral and fluorescence decay methods have been employed to determine the conformations of mono[6-......
Novel bicyclic isonucleosides, 2′-deoxy-2′ -nucleobase-5′-deoxy-1′ , 4′ : 3′ , 6′ -dianhydro- D-mannitol 10a-10c,......
The platinum (II) complexes of the [Pt (N4,N7-Ribavirin) (DMSO) Cl], [Pt (N4,N7-De-oxyribavirin) (DMSO) Cl] were obtaine......
We have developed an alternative route to synthesize Tn antigen. The synthetic product was characterized by IR, 1H-NMR ......
A new method for synthesis of 3-azido-3-deoxyxylofuranoside was described. D-ribose was methylated, then treated with m......
AIM:To determine whether 2-(3-carboxy-l-oxopropyl) amino-2-deoxy-D-glucose(COPADG),a derivative of D- amino-glucose,inhi......
Effects of{2-[(3-carboxy-1-oxoprogyl)amino]-2-deoxy-D-glucose}on human hepatocellular carcinoma cell
Aim:To study the effects of{2-[(3-carboxy-1-oxoprogy 1)amino]-2-deoxy-D-glu-cose(COPADG)on cultured human hepatocellula......
5-Fluorouracil concentration in blood, liver and tumor tissues and apoptosis of tumor cells after pr
AIM: To study the levels of 5-fluorouracail (5-FU) in plasma, liver and tumor in patients with hepatoceilular carcinoma ......
Metastaticrenalcellcarcinoma(RCC) isadiseasewithpoorprognosis, witha5 yearsurvivalbelow10% Becauseoflittleornoefficacyo......
The possible value of ~18F-FDG positron emission tomography/computerized tomography imaging in detec
Objective:To evaluate the clinical value with positron emission tomography/computerized tomography(PET/CT)imaging for th......
With a self-made near-infrared analytical instrument to blood and oxygen parameters in human brain, 80 cases in which 20......
穿心莲Andrographis paniculata Nees系爵床科须药草属一年生草本植物。已报导所含二萜内酯成分有穿心莲内酯(Andrographolide)、......
Studies on the Syntheses and Properties of 5′-Branched-sugar Isonucleosides and the Related Oligonuc
The chemistry of nucleosides and oligonucleotides is an actively investigated field in the search for new drugs. The syn......
本文对抗菌素10676进行了化学结构研究,结果表明:它是一个由2,6-二氨基-2,6-二脱氧-D-葡萄糖(2,6-diamino-2,6-dideoxy-D-glucose ......
在你刊今年第9期《穿心莲治疗菌痢化学成分与临床疗效的研究》一文中,我们对穿心莲的化学成分deoxyandrographolide 均译为脱羟基......
A new polyhydroxysteroidal glycoside,(20R,24R)-16-O-(4-O-methyl-2-acetamido-2-deoxy-β-D-galactopyranosyl)-24-ethyl- 5α......
Effects of 15-deoxy-△~(12,14)-prostaglandin J_2 on cell proliferation and apoptosis in ECV304 endoth
AIM: To investigate the effects of 15-deoxy-△12,14-prostaglandin J2 (15d-PGJ2) on cell proliferation and apoptosis in E......
作者利用国内丰富的鬼臼毒素,根据构效关系研究发现的4′-去甲表鬼臼毒素中4位这一较为有效的修饰位点,合成了4′-去甲表鬼臼毒素......
由Amadori在1926—1931年间发表的研究成果而得名的Amadori重排反应,迄今为止仍为人们所重视,是由于这个反应十分巧妙,应用甚广。......
Objective To study the chemical constituents from the stems of Marsdenia tenacissima.Methods The chemical constituents w......
Studies on sulfinatodehalogenation ⅫⅠ.Synthesis of 2-perfluoroalkyl-2-deoxy-D-glucose,mono- and poly
Sodium dithionite-initiated addition of R_FI(1)[R_F.=1a,Cl(CF_2)_4;1b,Cl(CF_2)_6;1c,Cl(CF_2)_6;1d,n-C_6F_(13);1e,n-C_8F......
The present paper reports the determination of the configuration and Conformation of 1’ -a-methoxy-2’ -deoxy-2’-β-f......
鬼臼酮、4β-羟基-2,3-不饱和鬼臼脂素和4-去氧-4β-叠氮基-2,3-不饱和鬼臼脂素在不同介质中分别转变为脱氢鬼臼脂素、4-去氧脱氢......
Two new coenzyme B12 analogues, 2’,5’-dideoxycytidylcobalamin (2a) and 2’,5’-dide-oxyuridinylcobalamin (2b), and tw......
The important intermediate for syntheses of various anti-HIV nucleoside analogues, methyl 2,3-dideoxy-3-fluoro-6-O-(p-m......
RNase A catalyzes the hydrolysis of ribonucleic acids to form oligonucleotide fragments containing pyrimidineribonucleo......
A series of novel N-[（p-substituted phenyl）dialkoxyphosphoryl]methyl-2-amino-2-deoxy-1,3,4,6-tetra-O-acetyl-β-D-glucopyra......
Studies on the Compounds of d4T Combined with Nitric Oxide Donors and Nitric Oxide Synthase Inhibito
Stavudine, a potent anti HIV and AIDS related complex, is one of the Nucleoside Analogue Reverse Transcriptase Inhibit......
目的 合成异核苷掺入寡核苷酸并考察它们与互补序列的结合能力。方法 采用DNA固相合成仪合成寡核苷酸 ,通过热变性实验考察双链......
Methyl 3-deoxy-3-(diphenylphosphino)-4,6-O-benzylidene-α-D-altropyranoside (1) and methyl 2-deoxy-2-(diphenylphosphino......
Chiral Phosphine Ligands Derived from Sugars8. Crystal and Molecular Structure of Diphenyl (methyl 4
The crystal structure of the title compound, C26H27O6P, has been determined by single--crystal X-ray diffraction. The cr......
Chiral Phosphine Ligands Derived from Sugars 4.Crystal Structure of Methyl 4,6-O-Benzylidene-3-Deoxy
The crystal structure of the title compound 3--MBPA, C26H27O5P (Mr.= 450. 44 ). has been determined by single--crystal X......
THE PREPARATION OF CROSSLINKED N,O-CARBOXYMETHYL CHITOSAN RESINSAND THEIR ADSORPTION PROPERTIESFOR T
Crosslinked N, O-carboxymethyl chitosan resins which can selectively adsorb triglyceride, were prepared by the reaction ......
Recently, more attention has been attracted by intelligent drug delivery systems (DDS), because the release of drug can......
吡喃糖的1,2-及1,3-缩水内醚苄醚由相应的吡喃糖的C-2氧负离子(对1,3-缩水内醚是C-3氧负离子)与连有氯原子的C-1经分子内关环反应......
The first example of cyclodextrin dimer appending a macrocyclic polyamine spacer on the primary faces was synthesized v......
