bioavailability相关论文
Evaluation of the Bioavailability of Metals in Sediment from the Southern Coastal Wetland of the Qia
Metal pollution has become an major issue governing the wetland ecosystem health. The southern coastal wetland of the Qi......
Due to its safety,convenience,low cost and good compliance,oral administration attracts lots of attention.However,the ef......
The seeds of Nigella sativa Linn.(Ranunculaceae), commonly known as Black cumin, are predominantly used as carminative, ......
Herein,the purpose of this study is to evaluate the effects of kaempferol on bioavailability and pharmacokinetics of nif......
Use of Tenax extraction for assessing bioavailability and toxicity of hydrophobic contaminants in se
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Predicting the bioavailability of polybrominated diphynel ethers (PBDEs) in soil by earthworms using
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Passive sampling of contaminated sediment for PCBs by headspace solid-phase microextraction (HS-SPME
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Stable Cu isotope(65Cu)was complexed with various representative dissolved organic carbon(DOC)sources,including coastal ......
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Bioavailability of polychlorinated dibenzo-p-dioxin / dibenzofurans (PCDD/Fs) in field collected sed
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Purpose Previous studies show that application ofbiochar can reduce the bioavailability of heavy metals in soil.A plant ......
Objectives: The objective of this investigation was to optimize an effective SMEDDS formulation for Rh1 to improve its i......
Chitosan-Modified PLGA Nanoparticles as Drug Delivery Carrier for Modulating P-Glycoprotein of Enter
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Poly(ε-benzyloxycarbonyl-L-lysine)-grafted branched polyethylenimine as efficient nanocarriers for i
Oral delivery is regarded as the most convenient and economical method of drug delivery[1].Unfortunately,approximately 5......
Resveratrol (3,5,4-trihydroxystilbene),a plant stilbenpolyphenol,represents various health benefits,such as anti-oxidant......
To prepare fenofibrate nanoliposome(FNB-Nanolipo)and investigate its characterizations,oral pharmacokinetic profiles as ......
Because of the total lack of toxicological data,so far no risk assessment exists for arsenolipids,which are frequently p......
Phytoremediation is a sustainable, cost-effective and environmental-friendly remediation strategy.Heavy metal (loid)s in......
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By pot experiment,the heavy metal speciation in sewage sludge and its effects on plant in two contrasting soils have bee......
SELF-EMULSIFYING WITH SOLID CARRIERS DRUG DELIVERY SYSTEMS(SESC)OF ANIRACETAM:FORMULATION OPTIMIZATI
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Brefeldin A is a secondary metabolite of Ascomycetes species.It was first isolated in 1958 by Singleton from Penicillium......
Development and characterization of mucoadhesive buccal films containing phospholipid-bile salts-mix
Cucurbitacin B (Cu B),a potent anti-cancer agents,suffers with the problems of gastrointestinal side effects and non-spe......
Development of hydrophobic drug EVT lyophilized nanosuspension for enhanced dissolution rate and ora
Objectives EVT,a strong antagonist to P2X7 receptor for non-steroidal anti-inflammatory was discovered through high-thro......
EFFECT OF POLYVINYLPYRROLIDIONE(PVP K30)ON SOLUBILITY AND BIOAVAILABILITY OF CURCUMIN IN SOLID DISPE
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Baicalein,a natural flavonoid mainly extracted from Radix Scutellaria,has comprehensive pharmacologic actions such as an......
Comparative study on the properties of nanoemulsion and liposome loaded with lycobetaine for enhance
In the previous report,lycobetaine(LBT)loaded nanoemlusion(NE)was found to increase the bioavailability than free drug.H......
Over the last decades, the formulation of drugs as nanocrystals has successfully evolved into a mature drug delivery str......
Pharmacokinetics and bioavailability of Chlorogenic acid from LoniceraeJaponicaeFlos following diffe
OBJECTIVE Chlorogenic acid (ChA) is proposed as one of the main bioactive compounds ofLoniceraeJaponicaeFlos (LJF).To st......
OBJECTIVE This study reports a promising approach to enhance the oral delivery of nuciferine(NUC),improve its aqueous so......
Objective: To improve the bioavailability of resveratrol,a poorly water soluble polyphenolic compound,via a novel formul......
The purpose of this study was to evaluate the increased physicochemical characterization,in vitro release,enhanced absor......
Objectives The aim of the present study was to prepare microcapsules for the oral delivery of realgar nanoparticles (RN)......
Preparation and pharmacokinetic studies of puerarin nanocrystals and microcrystals after oral admini
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Mesoporous carbon as a poorly water soluble drug carrier for increasing the oral bioavailability and
Objective: Mesoporous carbon (MC) was as cartier of poorly water-soluble drugs for enhancing the permeation of through C......
Extractive biodegradation of diphenyl ethers in a cloud point system:Pollutants bioavailability enha
The biodegradation of diphenyl ethers (DEs) in the environment is limited by their high hydrophobicity.The enhancement o......
Carvedilol is an anti-hypertensive agent with nonselective β-blocking and α1-blocking activities.It has been widely us......
Multi-biological activities of curcumin and its analogues connecting structure-activity relationship
Curcumin,the yellow pigment present in the Indian spice turmeric derived from Curcuma longa,associated with curry powder......
Insulin sensitizing medicines are currently limited, and identification of new drug candidate is a challenge.Protein tyr......
The influence on the pharmacokinetics of polymorphic rifampicin by the change of dosage form and rou
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Objective:A big amount of surfactants were in need to form microemulsions and consequent toxicity restricted the applica......
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The purpose of this study was to investigate the effect of paclitaxel in combination with 20 (s)-ginsenoside Rg3 on its ......
Microenvironment pH-stimulated multilayer pellets to increase in vitro dissolution and enhance in vi
Many drugs have pH-dependent solubility,the human gastrointestinal tract cannot provide corresponding acidic or alkaline......
Fenofibrate Nanoliposome: Preparation and Its Inhibition Effects on Nonalcoholic Fatty Liver Disease
Objective: To prepare fenofibrate nanoliposome (FNB-Nanolipo) and investigate its characterizations, oral pharmacokineti......
