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30. Knockdown of IGF-IR by Antisense Oligodeoxynucleotide auguments the sensitivity of bladder cance
AND AIM: Transitional cell carcinoma (TCC) of the bladder represents the fifth most prevalent malignancy in Western popu......
目的:采用分子对接法筛选酪氨酸蛋白激酶受体B2（EphB2）小分子抑制剂，研究其对皮肤鳞状细胞癌（CSCC）的影响及可能机制。方法:利用Schrodi......
肺纤维化是一种以肺实质重塑和胶原沉积为特征的不可逆性间质性肺病。近年来，不明原因导致的肺纤维化发病率和病死率呈上升趋势，其发......
目的:评价异丙酚对小鼠神经干细胞增殖的影响及转录因子特异性蛋白1(Sp1)-表皮生长因子受体(EGFR)-蛋白激酶B(Akt)信号通路在其中......
表皮生长因子受体（EGFR）基因作为重要的肿瘤驱动基因，在非小细胞肺癌（NSCLC）的发生、发展中发挥着重要作用。奥希替尼作为最新一代的EGF......
Dopamine D4 Receptor Gene Associated with the Frontal-Striatal-Cerebellar Loop in Children with ADHD
Attention deficit hyperactivity disorder (ADHD) is a common childhood neuropsychiatric disorder that has been linked to ......
Post-translational degradation of protein plays an important role in cell life.We employed chimeric molecules (dihydrote......
The diverse and contrasting effects of using human prostate cancer cell lines to study androgen rece
The androgen receptor (AR) plays an important role in the development and progression of prostate cancer (PCa).Androgen ......
Advanced prostate cancer is responsive to hormone therapy that interferes with androgen receptor (AR) signalling.However......
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The Plasma Membrane Protein PREN is a Potential Receptor Candidate of Fungal Elicitor PeaT1 which In
Protein elicitor PeaT1, which was originally isolated from Alternaria tenuissima, could induce systemic acquired resista......
Grass carp reovirus(GCRV),the representative strain of Aquareovirus-C,serves as a model for studying the pathogenesis of......
In vitro effect of β-hydroxybutyric acid, leptin and insulin on leptin and its receptor mRNA express
Leptin is an adipocyte-derived hormone/cytokine that links nutritional status and hypothesized to function as a negative......
Gefitinib with or without transarterial infusion chemotherapy(cisplatin)for large non-small cell lun
Objective Purpose: To retrospectively investigate the safety and benefit of gefitinib plus transarterial infusion(TAI)th......
Cone-beam breast computed tomographic features associated with HER2/neu overexpression in patients w
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In the primary visual cortex,activity of neurons evoked by stimuli within the classical receptive field (CRF) can be mod......
Objective The epileptiform activity was induced by perfusing GABAA receptor antagonist bicuculline (Bic, 30 μmol/L) in ......
The airway preganglionic parasympathetic motoneurons (APPMs) supply the essential excitatory drive to the postganglionic......
Aim: To investigate the expression and function of B ceil-activating factor (BAFF) and its receptors (BCMA, TACI, and BA......
Caspr1 is the host receptor for pathogenic Escherichia coli to penetrate the blood-brain barrier and
Escherichia coli (E.coli) is the leading cause of neonatal gram-negative bacterial meningitis, but the pathogenesis of E......
Therapeutic effects of TACI-Ig on rats with adjuvant-induced arthritis via regulating T cell-mediate
OBJECTIVE To investigate the effects of TACI-Ig, a recombinant fusion protein that modulates B and T cells activation by......
The Inhibitory Effect of ATRAP, an Ati Receptor-Associated Protein,on Vascular Smooth Muscle Cell Gr
The mechanism by which ATRAP, a novel Ati receptor-associated protein, interferes with Ati receptor-mediated signaling r......
OBJECTIVCE Schizophrenia is a chronic, debili tating psychotic mental disorder.Many studies suggest that dopa mine D3 re......
Acid Sphingomyelinase Mediated 50 Hz Magnetic Field Induced-EGF Receptor Clustering in Cultured Cell
Background: Growing evidence indicated that exposure to extremely low frequency electromagnetic fields (ELF MF), especia......
β1-adrenoceptor autoantibodies from DCM patients enhance the proliferation of T lymphocyte through t
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Technetium-99m Radiolabeled S-acetyI-MAG3-K237: Preparation,Identification and Scintigraphy in Hepat
OBjective: Vascular endothelial growth factor receptor-2(KDR)is one of the potential ideal target for molecular imaging ......
Asymmetric Expression of Melatonin Receptor mRNA in Bilateral Paravertebral Muscles in Adolescent Id
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Histaminergic neurons reside in the tuberomammillary nucleus of the posterior hypothalamus where histamine is synthesize......
Abnormal expression of BLyS/APRIL and receptors in synovium tissue mediate T cell responses in adjuv
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Background and aims:Vascular calcification is common in people with diabetes and its presence predicts premature mortali......
IE-PP27:Selective Anion and Cation Receptors Based on Cyclic Triamides:Facile One-step Synthesis and
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Clostridium perfringens ε-toxin (ETX) is the main toxin resulting in enterotoxemia of sheep and goats. ETX can cause le......
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Expression and role of adrenomedullin and its receptor in patients with chronic obstructive pulmonar
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研究显示，过氧化物酶体增殖物激活受体（peroxisome proliferator-activated receptor，PPAR）除了促进脂肪形成和胰岛素稳态外，还参与许多......
有效避免二次卒中预防方案（Prevention Regimen for Effectively Avoiding Second Strokes，PROFESS）试验是迄今规模最大的一项卒中二......
Diabetic nephropathy(DN)is one of the most common complications of diabetes.It is an important cause of diabetes disabil......
Paeoniflorin-6′-O-benzene sulfonate ameliorates progression of adjuvant-induced arthritis by inhibit
OBJECTIVE Aryl hydrocarbon receptor(Ahr)is thought to be a crucial factor that regulates immune responses,which may be i......
Salvia miltiorrhiza-asarum ointment combined with Chinese medi-cal massage alleviates symptoms of os
OBJECTIVE:This study investigated the effect of salvia miltiorrhiza-asarum ointment (SMAO) plus Chinese medical massage ......
Molecular genetic analysis is an integral part of colorectal cancer(CRC)management.The choice of systemic therapy for CR......
