前列腺癌是老年男性最常见的恶性肿瘤之一。前列腺癌患者一旦发生远处转移往往预后较差，而50%以上的中国前列腺癌患者在初诊时已发......

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Purpose To prospectively evaluate the safety and local efficacy of percutaneous conformal cryoablation for patients with......

Aims: To find specific magnetic resonance imaging(MRI)features to differentiate metastatic ovarian tumors fromprimary ep......

Objective Pulmonary benign metastasizing leiomyoma(PBML)is rare,usually occurs in women during reproductive years after ......

Background:Metastasisisaleadingcauseofmortalityforosteosarcomapatients. MethodsandResults:microRNAmicroarraywasusedtoass......

Purpose: Ras-specific guanine nucleotide-releasing factor 2(RasGRF2) is a member of the guanine nucleotide exchange fact......

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Objective:Apatinib is an oral TKI targeting VEGFR-2.Single-agent apatinib treatment has been shown to produce an objecti......

Metastatic bone disease of the distal extremities,also known as acrometastasis,is very rare.Thus,there is very limited i......

Secondary cancers of the liver are more than twenty times more common than primary tumors and are incurable in most case......

目的探讨区域性淋巴结清扫治疗转移性去势抵抗性前列腺癌(mCRPC)的临床效果及安全性。方法回顾分析2015年8月至2021年5月于复旦大......

BACKGROUND The spine is the most common location of metastatic diseases.Treating a metastatic spinal tumor depends on ma......

Objective:Bevacizumab has an important and evolving role in improving outcomes in patients with metastatic colorectal ca......

There is a lack of high-quality,large-scale,real-world evidence from patients with metastatic colorectal cancer(mCRC),es......

BACKGROUND Melanoma is uncommonly found in lymph nodes,subcutaneous tissue,or visceral organs without a primary lesion,w......

Pancreatic cancer is one of the solid tumors with the worst prognosis.Five-year survival rate is less than 10%.Surgical ......

AIM:To assess subcellular localization of KL-6 mucinand its clinicopathological significance in colorectalcarcinoma as ......

AIM: To compare gemcitabine-based combination therapy and gemcitabine (GEM) alone in patients with advanced pancreatic c......

BACKGROUND: Duodenal gastrointestinal stromal tumors, which are rare, comprise 3%-5% of all gastrointestinal stromai tum......

AIM: To study the differential gene expression profiles of target cells in primary gastric cancer and its metastatic lym......

Recent studies suggest that PRL-3 is involved in the metastasis of colorectal cancer, but the mechanism concerning that ......

AIM: To examine the usefulness of a new tapered metallic stent(MS) in patients with unresectable malignant hilar bile du......

Although ipilimumab has been shown to improve survival in patients with metastatic melanoma and cause regression of meta......

Pancreatic cancer is one of the most lethal human malignancies, partly because of its propensity for metastasis. However......

目的:评估大肠癌患者血清MMP-7含量及其临床意义。方法:术前应用免疫酶联反应技术对50例大肠癌患者以及36例健康对照者的血清MMP-7......

Metastatic colorectal cancer (mCRC) continues to be counted as a major health problem. The introduction of newer cytotox......

Objective:The aim of our study was to investigate the effect of Pin1 on the expression of MMP-2 and MMP-9 in human color......

Objective:It remains unclear whether simultaneous use of two chemotherapeutic drugs is better than sequential use.This t......

AIM To establish clone cells with different metastaticpotential for the study of metastesis-related mechanisms.METHODS ......

In the recent decades,the incidence of hepatocellularcarcinoma(HCC)has been found to be increasing in malesin some coun......

Objective: To study the mechanism, clinical characteristics, therapy regimens, and survival of cervical carcinoma metast......

Direct administration of drugs and genes to the lungs by pulmonary delivery offers a potential effective therapy for lun......

Gene transcription mechanisms are critical control points for cell function and differentiation as well as disease patho......

Tumors of the cardiac conduction system(CCS) have rarely been reported. The CCS from 198 cardiac-related deaths(Group Ⅰ......

Many studies have demonstrated the impact of UGT1A1 on toxicity of irinotecan. In particular, patients bear-ing UGT1A1*2......

Colorectal cancer(CRC) is one of the most common cancers and a leading cause of cancer-related mortality worldwide. Alth......

Gastro-entero-pancreatic neuroendocrine neoplasms(GEPNENs) represents a various family of rare tumours. Surgery is the f......

Surgical resection is the only option of cure for patients with metastatic colorectal cancer(CRC). However, the risk of ......

Objective: The aim of the study was to investigate the correlation of zinc-finger protein 217(ZNF217) gene expression wi......

Objective To investigate the role of matrix metalloproteinase-1(MMP-1)/proteaseactivated receptor-1(PAR-1) signaling in ......

The authors report herein a series of 3 patients with caseous mitral annular calcifications (MAC). One of the patients p......

AIM:To report the clinical impact of adrenal endoscopic ultrasound fine-needle aspiration(EUS-FNA)in the evaluation of p......

·Clinical history for diagnosis of dementia in men:Caerphilly Prospective Study男性痴呆诊断临床病史:卡尔菲利前瞻性研究......

Ectopic mineralization- inappropriate biomineralization in soft tissues- is a frequent finding in physiological aging pr......

The U.S.Food and Drug Administration today approved Tresiba(insulin degludec injection)and Ryzodeg70/30(insulin degludec......

Metastatic human HCC model is needed for the studies onmechanism and intervention of metastatic recurrence,Byusing orth......

Bonemetastasisofmammarytumoriscommoninclinicandcomprehensivetreatmentconcentratedonchemotherapyissuggested．Short－termrelie......

Objective Increase therapeutic effective rat e of post-perineum malignant carcin oma and decrease side effects.Method In......

The prognosis of patients with HCC still remainsdismal.The life expectancy of HCC patients is hardto predict because of......