糖尿病是一组病因病理与临床特征高度异质性的疾病。1型糖尿病（T1DM）在遗传学、免疫学、代谢学及治疗学等方面呈现不同的内在型与临......

The distinct characteristics of γδ T cells determine their vital roles in the formation of local immune responses and ......

Background:Insect herbivory has profound impacts on ecosystem processes and services.Although many efforts have been mad......

Organoids are three-dimensional culture systems generated from embryonic stem cells, induced pluripotent stem cells, and......

This study is a detailed analysis of Speculation Game,a simple agent-based model of finan-cial markets,in which the roun......

CO2 + O2 in-situ leaching (ISL) of sandstone-type uranium ore represents the third generation of solution mining in Chin......

Petrophysics of coals directly affects the development of coalbed methane(CBM).Based on the analysis of the representati......

Single-cell genomics provides substantial resources for dissecting cellular heterogeneity and cancer evolution. Unfortun......

The influence of closed and open surface flaws on the stress distribution and failure in rock specimens is investigated.......

Astrocytes are multifunctional brain cells responsible for maintaining the health and function of the central nervous sy......

Nonalcoholic fatty liver disease (NAFLD) affects about a quar-ter of the world\'s population and poses a major health ......

It is of great significance to study the spatial distribution patterns and petrophysical com-plexity of volcanic vesicle......

We present lithofacies classifications for a tight gas sandstone reservoir by analyzing hierarchies of heterogeneities.W......

Examining the travel time variability(TTV)of buses,passenger cars and taxis is important for the purpose of obtaining re......

Positively skewed shape is one of the most common features imprinted in hydrologic response function such as unit hydrog......

In deep geological repositories for spent fuel and high-level radioactive waste (SF/HLW), a great deal of gas will be pr......

Heterogeneity of reservoir may affect the development of oil production obviously.Polymer flooding could improve the pas......

In many cities,urban development has reached the fringes of old industrial and mixed industrial/residential areas,where ......

Objective:Toinvestigatethespatialandtemporaldynamicsofmorphologyandproliferationofreactiveglialcellafterspinalcord injur......

Objective In lung cancer,biomarker analyses and treatment decisions are often made based on small tumor biopsies.This is......

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Objective we summarize the most important recent findings in the field of circulating tumor DNA,focusing on its signific......

Objective To investigate the degree,production mechanism and clinical significance of three-dimensional tumor microvascu......

Purpose The purpose of the study was to evaluate whether CT histogram and texture features can help to predict early rec......

Objectives: To quantitatively assess the value of iodine concentration of spatial different distribution in malignant an......

Objective: To investigate spatial heterogeneity of Ki-67 index in low-grade and high-grade gliomas,to explore whether th......

Objective Due to biological heterogeneity,the therapeutic response of TKI showed significance difference between primary......

Objective Breast phyllodes tumors(PTs)are breast fibroepithelial lesions that are subtyped to benign,borderline or malig......

目的 Lungcanceristhemostcommonmalignancyandleadingcauseofcancermortalityintheworld.Despiteadvancesinmultipletherapies,it......

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Background: Cancer is complex due to the extensive heterogeneity both between and within tumors.The cancer progression a......

Objective: To analyze the heterogeneity of in frequent symptoms among Chinese children with methylmalonicaciduria (MMA)o......

Background: DNA methylation plays pivotal roles in gene regulation during tumor initiation and progression, and many can......

Currently,the long-term survival of adult B-ALL patients is less than 50%.To improve the cure and survival rates of adul......

Background: The purpose of this study was to evaluate the prognostic implication ofasphericity(ASP);spatial irregularity......

The existence and identification of leukemia stem cells in adult acute B lymphoblastic leukemia(B-ALL)remain controversi......

Neuronal microcircuitry represents the communications between various individual neurons,mainly consisting of chemical s......

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This paper investigates the influence of heterogeneity on mechanical and acoustic emission(AE)behaviors of stratified ro......

In view of their critical function in metastasis,characterization of single circulatingtumor cells(CTCs)can provide impo......

It was known previously that both excitatory and inhibitory neuronal networks could achieve robust synchronization only ......

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Department of Industrial Systems Engineering,National University of Singapore Wiener process plays a crucial role in deg......

Combining datasets collected from similar studies becomes increasingly popular in biomedical research to achieve larger ......

Purpose-This study explores the mediation of strategic ambidexterity on the characteristics of TMT heterogeneity and fir......