Antiviral相关论文
Antiviral,immunomodulatory,and anticoagulant effects of quercetin and its derivatives:Potential role
The coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infe......
α-Lipoic Acid Exerts Its Antiviral Effect against Viral Hemorrhagic Septicemia Virus (VHSV) by Promo
Viral hemorrhagic septicemia virus (VHSV),belonging to the genus Novirhabdovirus,Rhabdoviridae family,is a causative age......
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus.As an emerging virus,CHIKV imposes a threat to public health.Cu......
临床上经常遇到结核病（TB）合并丙型肝炎病毒（HCV）感染者需要同时治疗。当抗HCV和抗TB药物联用时需要考虑药物-药物之间的相互作用（DDIs）......
Ge Gen Decoction (GGD),a Traditional Chinese Medicine prescription,is mainly used to treat infectious respiratory diseas......
2\',3\'-dideoxyguanosine (DoG) has been demonstrated to inhibit duck hepatitis B virus (DHBV) replication in vivo in......
25-Epimeric Steroids with Antiviral activity against RSV from the South China Sea Gorgonian Echinogo
...
SIRT6 Inhibitor,OSS_128167 Restricts HBV Transcription and Replication through Targeting Transcripti
Hepatitis B virus(HBV)is a major public health threat and leading to end-stage liver diseases,such as hepatitis and hepa......
AIM The shortage of anti-viral drugs urge us to look for new lead compounds for developing new anti-influenza viral drug......
AIM Influenza A virus (IAV) resistance to available antiviral agents urges us to discover new drugs.Natural flavonoids h......
...
Synthesis of Phosphorylated Derivatives of 2′,3′-O-Isopropylidene Adenosine: Their in vitro and in v
...
...
目的 探讨综合护理干预在改善丙型肝炎患者抗病毒治疗依从性中的作用。方法 回顾性分析我院2018年11月至2019年12月收治的80例丙型......
The COVID-19 pandemic has caused millions of deaths and hundreds of millions of confirmed infections worldwide. This pan......
OBJECTIVE Human metapneumovirus(hMPV)is semblable to respiratory syncytial virus(RSV)which causes respiratory infections......
Clinical characteristics and effectiveness of antiviral agents in hospitalized children with infecti
Importance::The clinical characteristics of infectious mononucleosis (IM) in Chinese children have not been evaluated in......
Hepatitis C virus treatment failure:Clinical utility for testing resistance-associated substitutions
The hepatitis C virus has a high mutation capacity that leads to the emergence of resistance-associated substitutions(RA......
Can remdesivir and its parent nucleoside GS-441524 be potential oral drugs?An in vitro and in vivo D
Remdesivir (RDV) is the only US Food and Drug Administration (FDA)-approved drug for treating COVID-19.However,RDV can o......
Bats are a potential natural reservoir for SARS-CoV-2 virus and other viruses detrimental to humans.Accumulated evidence......
Honeysuckle has been used in the treatment of influenza virus infection for thousands of years in China.However,its main......
Generation of A Stable GFP-reporter Zika Virus System for High-throughput Screening of Zika Virus In
Zika virus(ZIKV) is associated with severe birth defects and Guillain-Barre′ syndrome and no approved vaccines or speci......
Long noncoding RNA AANCR modulates innate antiviral responses by blocking miR-210-dependent MITA dow
Viral infection induces the initiation of antiviral effectors and cytokines which are critical mediators of innate antiv......
Kaempferol inhibits Pseudorabies virus replication in vitro through regulation of MAPKs and NF-κB si
Pseudorabies virus(PRV),in the family Herpesviridae,is a pathogen of Aujeszky’s disease,which causes great economic los......
Combination therapy using low dose radiation,plasma exchange,and a robust antiviral may induce syner
Recent studies confirm that current antiviral drugs are not fully effective on coronaviruses.Our research team introduce......
Dual inhibition of COVID-19 spike glycoprotein and main protease 3CLpro by Withanone from Withania s
Objective:To identify the safe and effective natural inhibitors of spike glycoprotein and main protease 3CLpro using pot......
Identification of Aristolactam Derivatives That Act as Inhibitors of Human Immunodeficiency Virus Ty
Despite the success of antiretroviral therapy(ART),efforts to develop new classes of antiviral agents have been hampered......
With advances in the management and treatment of advanced liver disease,including the use of antiviral therapy,a simple,......
Combination therapy with peginterferon (pegIFN)-α and ribavirin (RBV) has been the standard of care (SOC) for chronic h......
Hepatitis B virus(HBV) circulates in blood and replicates in the presence of quasispecies. During HBV replication, HBV D......
The Change of Quantitative of HBeAg Can Predict the Efficacy of Peg-IFN-α 2a in HBeAgpositive CHB Pa
Objective To investigate the quantitation of hepatitis B e antigen(HBeAg)at week 24 in predicting the efficacy of pegyla......
Direct-acting antiviral agents(DAAs)for hepatitis C virus(HCV)infection are one of the major advances in its medical tre......
Are metabolic factors still important in the era of direct antiviral agents in patients with chronic
The high rate of sustained viral response(SVR)to boceprevir or telaprevir-based triple therapy in hepatitis C(HCV)-relat......
Objective To evaluate the therapeutic effects of telbivudine and entecavir on patients with chronic hepatitis B by meta-......
Investigation of antiviral efficacy in patients with chronic hepatitis C originating from a same blo
Objective To investigate the antiviral efficacy of standard treatment with interferon(IFN)-α2b and ribavirin(RBV)in pat......
Risk factors for liver-related mortality in chronic hepatitis C patients:A deceased case-living cont
AIM:To investigate the risk factors for liver-related mortality in chronic hepatitis C(CHC)patients.METHODS:All deceased......
The ideal endpoint of hepatitis B virus(HBV)antiviral therapy is HBsAg loss,a difficult goal to obtain,especially in HBe......
Hepatitis C virus(HCV) infection is a common chronic liver disease worldwide.Non-alcoholic fatty liver disease and insul......
AIM:To investigate the utility of phosphorus-31(31P)magnetic resonance spectroscopy(MRS)as a noninvasive test for assess......
AIM:To determine the frequencies of mutations that cause inherited monogenic liver disorders in patients with chronic he......
New nucleos(t)ide analogues(NAs) with high genetic barrier to hepatitis B virus(HBV) resistance(such as entecavir, tenof......
Human immunodeficiency virus(HIV)and hepatitis C virus(HCV)share the same transmission routes;therefore,coinfection is f......
A new treatment paradigm for hepatitis C is that the treatment must include an existing direct-acting antiviral agent, n......
AIM: To describe a population of outpatients in Chinainfected by hepatitis B virus(HBV) and/or hepatitis C virus(HCV), a......
Treatment of chronic hepatitis B(CHB) has markedly improved in the last 15 years due to the availability of direct antiv......
Chronic hepatitis C is a public health problem worldwide.Unfortunately,not all patients may benefit from antiviral thera......
Hepatitis B surface antigen levels during natural history of chronic hepatitis B: A Chinese perspect
AIM: To determine the baseline hepatitis B surface antigen(HBsAg) levels during the different phases of chronic hepatiti......
Interplay between hepatitis B virus and the innate immune responses:implications for new therapeutic
Hepatitis B virus(HBV) infection is still a worldwide health problem;however,the current antiviral therapies for chronic......
Hepatitis C virus(HCV)infection is a global health problem,with an estimated 170 million people being chronically infect......
AIM:To investigate hepatitis B surface antigen(HBsAg)levels in patients with HBeAg-positive chronic hepatitis B(CHB)and ......
