目的：通过比较女性前牙反牙合患者乳牙期到替牙期（Ｄ－Ｍ期）与替牙期到恒牙期（Ｍ－Ｐ期）有限元分析结果，探讨软组织局部在不同阶段的生长发育特点。方法：用方差分析进行显著性检验。结果：鼻区与鼻下区在这两个阶段有相似的生长行为；下唇唇珠部在Ｄ－Ｍ期生长变化较Ｍ－Ｐ期明显，而下唇基部生长Ｍ－Ｐ期比Ｄ－Ｍ期明显；颏部软组织在Ｍ－Ｐ期的生长量较Ｄ－Ｍ期减小，以形状变化为主。结论：软组织不同部位在不同生长发育阶段的表现有所差异，在实施矫治时应予以关注。 Objective: To compare the results of finite element analysis (FEM) between primary dentition versus molar period (D-M period) and dentition period to permanent period (M-P period) Developmental characteristics. Methods: The variance test was used for significance test. Results: The nasal area and nasal area had similar growth behavior in these two stages. The growth of lower lip and lip in D-M phase was more obvious than that in M-P phase, M period was significant. The growth of chin soft tissue in M-P phase was smaller than that in D-M phase, with the change of shape being dominant. Conclusion: The performance of different parts of soft tissue in different stages of growth and development are different, and should be paid attention to in the implementation of orthodontic treatment.