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目的探讨儿童肾病综合征血脂系列变化情况。方法对处于疾病活动期的38例住院患儿,清晨空腹抽血,检测血脂系列。结果检测血脂系列比单测血总胆固醇的异常率高,载脂蛋白B100与总胆固醇呈正相关(r=0.648,P<0.01)。结论血脂系列测定更能全面、早期地反映患儿血脂变化情况,为正确使用降脂药,减轻高脂血症对肾小球等的损害,提供了客观依据。
Objective To investigate the changes of blood lipids in children with nephrotic syndrome. Methods Thirty-eight inpatients with active disease in the disease were enrolled in the study. Results The abnormal rate of total cholesterol in blood lipid test series was higher than that of single blood test. Apolipoprotein B100 was positively correlated with total cholesterol (r = 0.648, P <0.01). Conclusion The series of blood lipids can reflect the changes of blood lipid in children comprehensively and early, and provide an objective basis for the correct use of lipid-lowering drugs to reduce the damage of glomeruli by hyperlipidemia.