[目的 ]研究阿霉素对MGc 80 3胃癌细胞凋亡的诱导作用 .[方法 ]通过细胞涂片苏木精与伊红染色法、吖啶橙荧光染色法和琼脂糖凝胶电泳法 ,观察了阿霉素诱导MGc 80 3胃癌细胞凋亡的形态变化 .[结果 ]阿霉素能使MGc 80 3胃癌细胞出现典型的凋亡 .DNA电泳呈梯形带 ,进一步证实了光学显微镜所见 .[结论 ]阿霉素可诱导MGc 80 3胃癌细胞发生细胞凋亡 . [Objective] To study the induction effect of doxorubicin on apoptosis of MGc 80 3 gastric cancer cells. [Methods] Cell smears of hematoxylin and eosin staining, acridine orange fluorescence staining and agarose gel electrophoresis, observation Doxorubicin-induced morphological changes of apoptosis in MGc 80 3 gastric cancer cells. [Results] Doxorubicin can cause typical apoptosis in MGc 80 3 gastric cancer cells. DNA electrophoresis showed a trapezoidal band, which further confirmed the optical microscope. [ Conclusion: Doxorubicin can induce apoptosis in MGc 80 3 gastric cancer cells.