本文介绍了以CL-TBP萃淋树脂为萃取色层材料、盐酸作淋洗剂、从粗Sc_2O_3制取高纯Sc_2O_3的生产工艺。工艺过程包括粗Sc_2O_3溶解、柱上色层分离、草酸沉淀和灼烧等工序。其中,色层分离过程采用三根色层柱,料液经柱Ⅰ饱和后,钪与杂质得到初步分离,再经过柱Ⅱ,Ⅲ淋洗后,Sc_2O_3得到纯化,纯度达99.99％以上。该工艺操作简便、产品质量稳定、生产能力较大、钪回收率高,现已应用于一定规模的高纯Sc_2O_3生产。 In this paper, the production process of high purity Sc_2O_3 from crude Sc_2O_3 was introduced with CL-TBP extraction resin as extraction chromatographic material and hydrochloric acid as eluent. The process includes crude Sc_2O_3 dissolution, column color separation, oxalic acid precipitation and burning processes. Among them, the chromatographic separation process uses three chromatography columns. After the material is saturated with column Ⅰ, the scandium and impurities are separated initially. After the columns Ⅱ and Ⅲ are eluted, the Sc_2O_3 is purified with the purity of 99.99%. The process is simple, stable product quality, large production capacity, scandium recovery rate has been applied to a certain scale of high-purity Sc_2O_3 production.