勃起功能障碍(ED)与抑郁症有较高的相关性和并存率。患有ED与抑郁的男性也可能患有一些其他疾病,如糖尿病、高血压及心脏病。由于ED通常也是服用治疗这些疾病的药物的常见副作用,故这些患者的治疗依从性较差。枸橼酸西地那非对于各种原因所致之ED有效,提示其对抑郁所致的ED及使用5-羟色胺再摄取抑制剂导致的ED也同 Erectile dysfunction (ED) and depression have a higher correlation and coexistence rate. Men with ED and depression may also have other illnesses such as diabetes, high blood pressure and heart disease. Because ED is also a common side effect of taking medications to treat these conditions, these patients have poor adherence to treatment. Sildenafil citrate for various causes of ED is effective, suggesting that the ED caused by depression and the use of serotonin reuptake inhibitors lead to the same ED