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本文用大剂量天然α－干扰素治疗31例重症病毒性肝炎患者，并以既往和同期未用α－干扰素的49例患者作为对照，所有患者均未接受人工肝治疗。治疗结果表明：应用天然α－干扰素的31例患者存活今为64．5％（20／31）较对照组存活率28．6％（14／49）明显提高（P＜0．005）。治疗组中虽有部分患者出现发烧、白细胞及血小板减少，经适当处理多数患者仍可接受治疗。
In this paper, a large dose of natural interferon alpha treatment of 31 patients with severe viral hepatitis, and in the past and did not use interferon alpha in 49 patients as a control, all patients were not treated with artificial liver. The results of the treatment showed that the survival rate of 31 patients with natural α-interferon was 64.5% (20/31), which was significantly higher than that of the control group (28.6%, 14/49) (P <0.005). Although some patients in the treatment group had fever, leukopenia and thrombocytopenia, the majority of patients can still be treated after proper treatment.