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本文报告从大蒜中成功地纯化了一种简单有机硫化合物──阿藿烯(Z-Ajoene),并首次发现阿藿烯对多种体外培养的肿瘤细胞系有生长抑制作用,其机制是诱导肿瘤细胞凋亡(apoptosis)。阿藿烯诱导体外培养的HL-60白血病细胞系、Molt-4T淋巴瘤细胞系、MGC-803胃癌细胞系等多
This paper reports the successful purification of a simple organic sulfur compound, Z-Ajoene, from garlic and found for the first time that adecan has a growth-inhibitory effect on a variety of in vitro cultured tumor cell lines, the mechanism of which is induction. Apoptosis. Allergen-induced in vitro culture of HL-60 leukemia cell line, Molt-4T lymphoma cell line, MGC-803 gastric cancer cell line, etc.