采用苦瓜浸膏对昆明系雄性成年小白鼠进行阴囊涂擦,结果发现:部分睾丸曲细精管上皮排列紊乱,层次减少。精于细胞内出现较大的空泡,线粒体肿胀,变态期精子顶体膜增厚、皱缩。精子数量减少,活力下降及畸变率增高。说明苦瓜浸膏局部应用,可阻抗精子的阶段发育,达到男性抗生育力目的。 Bitter gourd extract was used to rub the scrotum of Kunming male adult mice. The results showed that the epithelium of some seminiferous tubules was disordered and the level was reduced. Proficient in the presence of large vacuoles in cells, swelling of mitochondria, metamorphosis sperm acrosome thickening, shrinkage. The number of spermatozoa decreased, vitality decreased, and the rate of distortion increased. This shows that topical application of bitter gourd extract can impede the development of spermatozoa and achieve the goal of male resistance to fertility.