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鹿茸是我国名贵中药材之一。具有“益气壮志”、“生精补髓、养血益阳”作用。鹿茸精是鹿茸的主要活性部分含有多种氨基酸、脂肪酸、核糖核酸、磷脂等物质,具有促进生长发育和强壮作用。强心健脑,延年益寿。我们根据鹿茸扶正的作用特点,从遗传毒理学角度,以小鼠骨髓嗜多染红细胞(PCE)微核率和染色体畸变(CA)率为指标,探讨鹿茸精对环磷酰胺(CP)诱发的遗传物质损伤有无保护作用。材料与方法鹿茸精系哈尔滨制药三厂出品,浓度、10％环磷酰胺由上海第十二制药厂生产。 (一)小鼠骨髓PCE微核试验
Antler is one of the most valuable Chinese herbal medicines in China. It has the functions of “best-strengthening ambition”, “spermatogenic medulla and nourishing yang”. Velvet antler is the main active part of velvet antler containing a variety of amino acids, fatty acids, RNA, phospholipids and other substances, with a role in promoting growth and strong. Strong mental health, longevity. Based on the characteristics of velvet antler, we studied the frequency of micronuclei and chromosomal aberration (CA) of mouse bone marrow polychromatic erythrocytes (PCE) from the perspective of genetic toxicology, and investigated the effects of pilose antler on cyclophosphamide (CP) induction. Damage to genetic material has no protective effect. Materials and methods Deer antler was produced by Harbin Pharmaceutical Factory No. 3, and its concentration and 10% of cyclophosphamide were produced by Shanghai No. 12 Pharmaceutical Factory. (I) Mouse bone marrow PCE micronucleus test