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Shy-Drager综合征又称原发性直立性低血压.是多以植物神经功能障碍为首发表现,随之可先后出现小脑、锥体外系、脑干和脊髓病变等一系列临床表现的一组综合征.本文对12例Shy-Drager综合征作一分析.1 临床资料1.1 一般资料 本组12例,男11例,女1例;年龄38~61岁,平均48.8岁;发病时年龄28~51岁,平均43.3岁;病程1~20年、平均5.4年.1.2 症状与体征1.2.1 植物神经功能障碍(1)血压差(指卧、立位血压差):收缩压平均相差6.4kPa,舒张压平均相差4kPa,其中1例卧位血压为16/8kPa,而立位为0;(2)晕厥7例;(3)少汗或无汗9例;(4)阳萎10例;(5)排尿困难10例,尿失禁7例.
Shy-Drager syndrome, also known as primary orthostatic hypotension, is the first manifestation of autonomic dysfunction, followed by a series of clinical manifestations of cerebellar, extrapyramidal, brainstem and spinal cord disease Syndrome in 12 cases of Shy-Drager syndrome for an analysis of 1.1 clinical data 1.1 General Information The group of 12 patients, 11 males and 1 female; aged 38 to 61 years, mean 48.8 years; the age of onset of 28 ~ 51 years old, average 43.3 years; duration of 1 to 20 years, an average of 5.4 years .1.2 symptoms and signs 1.2.1 autonomic dysfunction (1) blood pressure difference (referring to lying, standing blood pressure): systolic blood pressure average difference of 6.4kPa, The average diastolic blood pressure difference 4kPa, of which 1 case of supine blood pressure of 16 / 8kPa, and stand 0; (2) syncope in 7 cases; (3) little or no sweat in 9 cases; (4) impotence in 10 cases; ) Dysuria in 10 cases, urinary incontinence in 7 cases.