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目的:探讨眼附属器包括眼睑、眼眶、泪腺等部位黏膜相关淋巴组织淋巴瘤(lymphphoma of mucosa-associated lymph-oid tissue,MALT)的临床、病理学特征与治疗方法。方法:分析24例眼附属器MALT淋巴瘤的临床、病理学及免疫组化结果,以及手术后治疗与预后情况。结果:24例眼附属器MALT淋巴瘤患者经影像学检查后均行手术治疗,其中16例行放疗,2例行化疗。20例随访3mo~7a后均存活。结论:影像学检查可辅助诊断眼附属器MALT淋巴瘤、术后病理活检及免疫组化分型检查可确诊本病,眼结膜MALT淋巴瘤预后较好,伴全身淋巴瘤转移术后辅以化疗或放疗。
Objective: To investigate the clinical, pathological features and treatment of mucosa-associated lymph-oid tissue (MALT) in ocular adnexa including the eyelids, orbits and lacrimal glands. Methods: The clinical, pathological and immunohistochemical results of 24 cases of ocular adnexal MALT lymphoma were analyzed, and the postoperative treatment and prognosis were analyzed. Results: Twenty - four cases of MALT lymphoma with eye appendages were treated by surgery. Of them, 16 were radiotherapy and 2 were chemotherapy. 20 cases were followed up for 3mo ~ 7a after surviving. Conclusions: The imaging examination can aid in the diagnosis of ocular adnexal MALT lymphoma. Postoperative pathological biopsy and immunohistochemical typing can confirm the disease. The prognosis of conjunctival MALT lymphoma is good, with lymphoma metastasis after chemotherapy combined with chemotherapy Or radiotherapy.