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潘生丁(双嘧哌胺醇,哌醇定)系扩张冠状血管及抑制血小板聚集的药物,临床主要用于缺血性心脏病。近年来随着对潘生丁药理学研究进展,其临床用途日趋广泛,本文综述其在儿科的临床应用。一、药理作用 1.实验证明本药对冠状血管有较强的扩张作用,主要扩张冠状动脉的小阻力血管,能显著增加冠脉血流量,增加心肌供氧量,并可促进侧支循环形成。
Dipyridamole (dipyridamol, pipereolidine) Department of coronary blood vessels and inhibition of platelet aggregation drugs, clinical mainly for ischemic heart disease. In recent years, with the progress of pharmacological research on dipyridamole, its clinical use is more and more widely, this article reviews its clinical application in pediatrics. First, the pharmacological effects 1. Experiments show that the drug has a strong role in the expansion of coronary vessels, the main expansion of coronary artery resistance vessels, can significantly increase coronary blood flow, increase myocardial oxygen supply, and can promote the formation of collateral circulation .