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异位ACTH综合征的细胞分子学基础及与临床的联系王子梅陆召麟郭爱丽1928年,美国Brown首先报道了1例由小细胞肺癌引起的柯兴综合征,从而揭开了异位ACTH激素分泌研究的序幕[1]。此后陆续有相似病例报告。直到60年代初,由于肽类激素生化方面的研究...
The cellular and molecular basis of ectopic ACTH syndrome and its clinical connection Prince Mei Lu Lulin Guo Aili In 1928, Brown in the United States first reported a case of Cushing syndrome caused by small cell lung cancer, thus revealing the ectopic ACTH hormone secretion. The prelude to the study [1]. Since then there have been similar case reports. Until the early 1960s, due to the biochemical aspects of peptide hormones...