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目的:对序贯性血液净化治疗重度有机磷农药中毒患者的临床疗效进行分析。方法:资料选自2011年10月-2013年10月在我院救治的重度有机磷中毒患者64例,将所有患者随机分为研究组和对照组,两组均予以常规治疗,对照组在此基础上采用血液灌流治疗,研究组患者则予以血液灌流联合序贯性连续性静脉血液滤过治疗。分析两组患者的临床治疗效果。结果:分析两组患者治疗的基本情况,研究组应用呼吸机的时间、昏迷时间、住院时间、胆碱酯酶活性恢复的时间均少于对照组,两组数据的比较差异具有统计学意义(P<0.05);经过积极的治疗后,研究组患者死亡率为3.13%,对照组为18.75%,两组数据的比较差异具有统计学意义(P<0.05)。结论:予以重度有机磷农药中毒患者序贯性血液净化治疗,可有效的降低死亡率,临床效果显著,值得推广应用。
Objective: To analyze the clinical efficacy of sequential blood purification in patients with severe organophosphorus pesticide poisoning. Methods: The data were collected from 64 patients with severe organophosphate poisoning who were treated in our hospital from October 2011 to October 2013. All patients were randomly divided into study group and control group. Both groups were treated routinely. In control group, Based on the use of hemoperfusion therapy, the study group was given hemoperfusion and sequential sequential venous hemofiltration. Analysis of two groups of patients with clinical treatment. Results: The basic situation of the treatment of two groups of patients was analyzed. The time of recovery, coma, hospital stay and activity of cholinesterase in the study group were less than those in the control group. There was statistically significant difference between the two groups P <0.05). After active treatment, the mortality rate was 3.13% in the study group and 18.75% in the control group. The difference between the two groups was statistically significant (P <0.05). CONCLUSIONS: Sequential blood purification treatment for patients with severe organophosphorus pesticide poisoning can effectively reduce the mortality rate, and the clinical effect is significant, so it is worth popularizing and applying.