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目的探讨HA与DA方案联合应用治疗慢性粒细胞性白血病的临床效果。方法 2009年至2011年灵宝市第一人民医院收治的42例慢性粒细胞性白血病患者,给予HA或DA方案进行联合治疗,7 d为1个疗程,HA与DA方案交替进行,治疗3个疗程,2个疗程间间隔7~14 d,观察患者的完全缓解率、部分缓解率、无效率及治疗总有效率。结果 42例患者完全缓解32例,部分缓解7例,无效3例,完全缓解率为76.19%,部分缓解率为16.67%,无效率为7.14%,治疗总有效率为92.86%。结论 HA或DA方案联合治疗慢性粒细胞性白血病的临床效果较好,完全缓解率较高,是一种有效的治疗方法。
Objective To investigate the clinical effect of combination of HA and DA in the treatment of chronic myeloid leukemia. Methods Forty-two patients with chronic myeloid leukemia who were treated in Lingbao First People’s Hospital from 2009 to 2011 were given HA or DA regimen for combination therapy for 7 days for one course of treatment. HA and DA regimen alternated for 3 Course of treatment, two courses interval of 7 to 14 days, observed the patient’s complete remission rate, partial response rate, inefficiency and total effective rate. Results The complete remission rate was 42%, partial remission was 7 and ineffective in 3 of 42 patients. The complete remission rate was 76.19%, the partial remission rate was 16.67%, the inefficiency rate was 7.14%, and the total effective rate was 92.86%. Conclusions HA or DA regimen combined treatment of chronic myelogenous leukemia clinical effect is better, a higher complete remission rate, is an effective treatment.